Theoretical Modeling of Cyclically Loaded, Biodegradable Cylinders

Soares, João S.; Rajagopal, Κ. R.; Moore, James E.

doi:10.1007/978-0-8176-4411-6_4

Cited by 9 publications

(3 citation statements)

References 134 publications

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“…The relationship among them is:

where C is a time constant and I 1 and I 2 are the first and second strain invariants. In a constitutive model of the material, the strain energy is relevant to the degradation parameter through damage-based evolution of the shear modulus [ 60 , 71 ]. The relationship between shear modulus μ and initial shear modulus μ 0 is:

…”

Section: Mechanical and Degradation Performancementioning

confidence: 99%

The Development of Design and Manufacture Techniques for Bioresorbable Coronary Artery Stents

Wang

Pang

et al. 2021

Micromachines

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Coronary artery disease (CAD) is the leading killer of humans worldwide. Bioresorbable polymeric stents have attracted a great deal of interest because they can treat CAD without producing long-term complications. Bioresorbable polymeric stents (BMSs) have undergone a sustainable revolution in terms of material processing, mechanical performance, biodegradability and manufacture techniques. Biodegradable polymers and copolymers have been widely studied as potential material candidates for bioresorbable stents. It is a great challenge to find a reasonable balance between the mechanical properties and degradation behavior of bioresorbable polymeric stents. Surface modification and drug-coating methods are generally used to improve biocompatibility and drug loading performance, which are decisive factors for the safety and efficacy of bioresorbable stents. Traditional stent manufacture techniques include etching, micro-electro discharge machining, electroforming, die-casting and laser cutting. The rapid development of 3D printing has brought continuous innovation and the wide application of biodegradable materials, which provides a novel technique for the additive manufacture of bioresorbable stents. This review aims to describe the problems regarding and the achievements of biodegradable stents from their birth to the present and discuss potential difficulties and challenges in the future.

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“…The relationship among them is:

…”

Section: Mechanical and Degradation Performancementioning

confidence: 99%

The Development of Design and Manufacture Techniques for Bioresorbable Coronary Artery Stents

Wang

Pang

et al. 2021

Micromachines

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“…Our recent work has aimed to develop modeling tools of describing the process of degradation and erosion and of predicting the location and approximate time of loss of structural integrity. 56,[58][59][60][61][62] The modeling requirements (indicated by ovals in Fig. 4) begin with specification of mechanical support requirements.…”

Section: Summary Of Recent Efforts In Modeling Strain-accelerated Biomentioning

confidence: 99%

“…57 We have proposed a material property description that includes the effects of strain in accelerating biodegradation. 56,58,61 To illustrate our approach, we outline here a basic model in which the material, at fixed degradation, can be characterized with a neoHookean, purely elastic model. More complex material descriptions are possible, including other hyperelastic models or time-dependent viscoelastic behavior.…”

Section: Summary Of Recent Efforts In Modeling Strain-accelerated Biomentioning

confidence: 99%

Biodegradable Stents: Biomechanical Modeling Challenges and Opportunities

Moore

Soares

Rajagopal

2010

Cardiovasc Eng Tech

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Biodegradable implants show great potential in many areas of medicine, and have already demonstrated success in simple applications such as sutures. For more complex devices, such as vascular stents, there are considerable challenges associated with the use of biodegradable materials. These materials typically are weaker than the metals currently used to construct stents, so it is difficult to ensure sufficient strength to prop open the artery and alleviate symptoms acutely. It is even more challenging to design a stent that provides structural support for a predictable, appropriate time to facilitate artery healing. These challenges are evident when one considers that there are no biodegradable stents on the US market despite more than 20 years of development efforts. This review summarizes previous efforts at implementing biodegradable stents, discusses the specific challenges involved, and presents a recently developed biodegradable material modeling framework that can benefit this exciting field.

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Comparison of Numerical Model with Experimental Measurements for the Purpose of Testing Partially and Fully Biodegradable Stents

Filipović

2023

Bioceramics, Biomimetic and Other Compatible Materials Features for Medical Applications

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Theoretical Modeling of Cyclically Loaded, Biodegradable Cylinders

Cited by 9 publications

References 134 publications

The Development of Design and Manufacture Techniques for Bioresorbable Coronary Artery Stents

The Development of Design and Manufacture Techniques for Bioresorbable Coronary Artery Stents

Biodegradable Stents: Biomechanical Modeling Challenges and Opportunities

Comparison of Numerical Model with Experimental Measurements for the Purpose of Testing Partially and Fully Biodegradable Stents

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