In survey sampling, interest often centres on inference for the population total using information about an auxiliary variable. The variance of the estimator used plays a key role in such inference. This study develops a new set of higher-order constraints for the calibration of estimators of variance for various estimators of the population total. The proposed strategy requires an appropriate model for describing the relationship between the response and auxiliary variable, and the variance of the auxiliary variable. It is therefore referred to as a model-assisted approach. Several new estimators of variance, including the higher-order calibration estimators of the variance of the ratio and regression estimators suggested by Singh, Horn & Yu and Sitter & Wu are special cases of the proposed technique. The paper presents and discusses the results of an empirical study to compare the performance of the proposed estimators and existing counterparts.