The article proposes a methodology for studying the relationship of culture and institutions in economic processes, based on rethinking the relationship of economic culture and institutionalized forms of economic development in the framework of the intersubjective paradigm. It allows to go beyond traditional value-neutral and normative theories in understanding the development mechanisms of national economics. It focuses the research on a real variety of motives for the behavior of subjects and value-cognitive strategies for using resources to influence changes in the configuration of power and institutional structure, formal and informal institutions, as well as interaction models. The purpose of the study is to develop an approach that provides a systematic description of the endogenous relations of culture, institutions and economics within the framework of the intersubjective paradigm. The objective of the research is to propose a two-level approach to the analysis of endogenous relations of cultural and value variables, institutional and behavioral variables; to develop a holistic vision of the formation of the value-institutional system of the economy as a result of a compromise of interacting different actors; to justify the relevance and increasing importance of the implementation of ethicaloriented approach in the formation of institutional practices and in solving strategic problems. To substantiate the conclusions and positions, the methods of the constructivist approach, historical-logical and comparative analysis, methods of analysis of complex systems and scientific observation are used. The statements and conclusions formulated in the article contribute to the expansion of the problem field and to the deepening of theoretical ideas about the role of cultural and value variables and institutional variables in the formation of models of the development of national economies. The practical significance of the research results presented in the article is that it can be used in the development of programs and projects for the implementation of innovation changes in the economy.