Theranostic applications of stimulus-responsive systems based on carbon dots

Ghiasi, Behrad; Mehdipour, Golnaz; Safari, Nooshin; Behboudi, Hamidreza; Hashemi, Mohadeseh; Omidi, Meisam; Sefidbakht, Yahya; Yadegari, Amir; Hamblin, Michael R.

doi:10.1080/00914037.2019.1695207

Cited by 4 publications

(3 citation statements)

References 132 publications

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“…There are various purposes for using nanoparticles to make nanobiosensors, including increasing the surface to stabilize biomaterials and thus increasing sensitivity, catalyzing the process, large dynamic range, the possibility of reacting at low potentials, and helping the quick transfer of electrons from the active center of the electrode surface reaction in the electrochemical nanobiosensors [23]. Nanoparticles can be easily fabricated using chemical methods and react with the analyte in the sample, and their inherent properties, such as optical or magnetic properties, can be used [24,25]. Graphene and its derivatives are nanoparticles with unique properties and have many applications in nanobiosensors [26].…”

Section: Introductionmentioning

confidence: 99%

Properties and Applications of Graphene and Its Derivatives in Biosensors for Cancer Detection: A Comprehensive Review

et al. 2022

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Cancer is one of the deadliest diseases worldwide, and there is a critical need for diagnostic platforms for applications in early cancer detection. The diagnosis of cancer can be made by identifying abnormal cell characteristics such as functional changes, a number of vital proteins in the body, abnormal genetic mutations and structural changes, and so on. Identifying biomarker candidates such as DNA, RNA, mRNA, aptamers, metabolomic biomolecules, enzymes, and proteins is one of the most important challenges. In order to eliminate such challenges, emerging biomarkers can be identified by designing a suitable biosensor. One of the most powerful technologies in development is biosensor technology based on nanostructures. Recently, graphene and its derivatives have been used for diverse diagnostic and therapeutic approaches. Graphene-based biosensors have exhibited significant performance with excellent sensitivity, selectivity, stability, and a wide detection range. In this review, the principle of technology, advances, and challenges in graphene-based biosensors such as field-effect transistors (FET), fluorescence sensors, SPR biosensors, and electrochemical biosensors to detect different cancer cells is systematically discussed. Additionally, we provide an outlook on the properties, applications, and challenges of graphene and its derivatives, such as Graphene Oxide (GO), Reduced Graphene Oxide (RGO), and Graphene Quantum Dots (GQDs), in early cancer detection by nanobiosensors.

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Section: Introductionmentioning

confidence: 99%

Properties and Applications of Graphene and Its Derivatives in Biosensors for Cancer Detection: A Comprehensive Review

et al. 2022

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“…Different carbon-based materials are used in solar cells, supercapacitors, light-emitting diodes, sensors, food safety, ion detection, pharmacology, and hydrophobic coatings [1][2][3][4][5][6][7][8][9][10][11]. Fluorescent carbon dots (CDs) represent a new class of carbon nano-size materials, which are of great interest as potential competitors to traditional semiconductor quantum dots.…”

Section: Introductionmentioning

confidence: 99%

“…The quantum confinement effect, conjugated π-domains, surface states, and the state of surface-bonded fluorescent molecules or molecules inside nanoparticles, as well as the effect of enhanced cross-emission are considered [12,13]. Physicochemical properties and PL may be controlled by passivation and functionalization of CDs surface during synthesis [2,10]. Besides, the PL intensity of CDs can be enhanced due to exciton-plasmon interaction with metal nanoparticles (NPs).…”

Section: Introductionmentioning

confidence: 99%

Photoluminescence enhancement of carbon dots by Ag nanoparticles in thin-film hybrid structures

Shmagina

Konshina

Shcherbinin

et al. 2020

Surface Engineering

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The plasmon enhancement of carbon dots (CDs) photoluminescence (PL) in thin-film structures with metal nanoparticles is of interest in their practical applications in sensors and light-emitters. This paper investigates CDs in the thin-film structures with nanogranulated silver films with different thickness. CDs in an aqueous solution were precipitated by spin-coating over the surface of annealed Ag films coated previously by a polymer layer. The IR, optical density and PL spectra of free-CDs and in thin-film structures with Ag films were studied. The PL intensity enhancement of CDs was demonstrated in the thin-film structures with Ag films due to absorption cross-section enhancement and the action of the Purcell effect. The improvement of thin-film structures producing technology will contribute to PL enhancement of CDs and the development of new thin-film sensors, light-emitters and other devices on their base.

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Facile construction of fluorescent traceable prodrug nanosponges for tumor intracellular pH/hypoxia dual-triggered drug delivery

Chen

Xie

Pei

et al. 2022

Colloid and Interface Science Communications

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Theranostic applications of stimulus-responsive systems based on carbon dots

Cited by 4 publications

References 132 publications

Properties and Applications of Graphene and Its Derivatives in Biosensors for Cancer Detection: A Comprehensive Review

Properties and Applications of Graphene and Its Derivatives in Biosensors for Cancer Detection: A Comprehensive Review

Photoluminescence enhancement of carbon dots by Ag nanoparticles in thin-film hybrid structures

Facile construction of fluorescent traceable prodrug nanosponges for tumor intracellular pH/hypoxia dual-triggered drug delivery

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