Therapeutic abortion and ectopic pregnancy: alternative sources for fetal stem cell research and therapy in Iran as an Islamic country

Abstract

Regenerative medicine as a background of stem cell research and therapy has a long history. A wide variety of diseases including Parkinson's disease, heart diseases, multiple sclerosis, spinal cord injury, diabetes mellitus and etc. are candidate to be treated using different types of stem cells. There are several sources of stem cells such as bone marrow, umbilical cord, peripheral blood, germ cells and the embryo/fetus tissues. Fetal stem cells (FSCs) and embryonic stem cells (ESCs) have been described as the most potent stem cell source. Although their plurior multipotent properties leads to promising reports for their clinical applications, owning to some ethical and legal obstacles in different communities such as Muslim countries, care should be taken for therapeutic applications of FSCs and ESCs. Derivation of these cell types needs termination of pregnancy and embryo or fetus life that is prohibited according to almost all rules and teaches in Muslim communities. Abortion and termination of pregnancy under a normal

Effect of Uterine Arterial Chemoembolization Combined with Ultrasound-Guided Uterine Curettage on Cervical Pregnancy and Influencing Factors

“…The implantation of fertilized eggs in the cervix is often unstable, and most patients with cervical pregnancy abort within 20 weeks of pregnancy [ 14 , 15 ]. There are abundant blood vessels around the gestational sac, and the embryo will increase its vitality as the gestational age increases, thereby increasing the risk of miscarriage and hemorrhage in patients with cervical pregnancy [ 16 , 17 ].…”

Prospect of Stem Cell Therapy and Regenerative Medicine in Osteoporosis

“…Additionally, as a subset of stromal stem cells, they can be obtained from various tissue sources. Bone marrow derive MSCs (BM-MSCs) with high osteogenic differentiation capability are the most common types of MSCs which have been used for osteoporosis ( 20 , 24 , 134 – 136 ). Herein, accumulating evidence indicates that alternation in the molecular mechanisms which modulate osteoblast differentiation in MSCs will make the MSC therapies reliable and more effective for osteoporosis ( 105 , 137 – 139 ).…”

“…In this respect, there is no practical pharmaceutical cure (18). Recently, stem cell therapies have attained remarkable clinical consideration with a promising strategy for regenerative medicine and tissue engineering to treat various types of diseases including osteoporosis (19)(20)(21)(22)(23)(24)(25)(26). Herein, discuss the effects of stem cell-based therapies in osteoporosis is the main objective of this review.…”

COVID-19 Pathology on Various Organs and Regenerative Medicine and Stem Cell-Based Interventions

“…Nowadays, cell therapy and regenerative medicine as one of the assuring and modern therapies have been able to promote the function of organs involved in various disorders and trigger their real healing reactions. Hereupon, different cells, specifically various stem cells, can be applied ( Wong et al, 2013 ; Monsel et al, 2014 ; Mao and Mooney, 2015 ; Goodarzi et al, 2019 ). Therefore, the purpose of the current review is to highlight the effects of cytokine storms on different organs in COVID-19 individuals and how stem cells manage this phenomenon.…”