Therapeutic drug level of tacrolimus causing intracranial hemorrhage in a patient with renal transplant

Abstract

Tacrolimus is used in solid organ transplant patients to prevent rejection, and no case of intracerebral hemorrhage (ICH) has been reported till date. We report a case of 31‐year‐old man with diabetes and hypertension for ten years who had a renal transplant four years back; diagnosed with tacrolimus‐induced ICH.

Tacrolimus-Associated Cerebral Vasculopathy Presenting with Recurrent Intracerebral Hemorrhage

“…Only one similar case has been reported in a KTR till date. [ 5 ] However, recurrent ICH was never reported in the past. ICH may be a marker of tacrolimus-associated vasculopathy.…”