Therapeutic percutaneous aspiration of pancreatic pseudocysts

Barkin, Jamie S.; Smith, Franklin R.; Pereiras, R; Isikoff, Michael B.; Levi, Joé U.; Livingstone, Alan S.; Hill, Michael C.; Rogers, Arvey I.

doi:10.1007/bf01367668

Cited by 56 publications

(13 citation statements)

References 4 publications

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“…Other studies, however, have shown that neither a history of smoking [10, 30] nor continued smoking [31] were risk factors for restenosis after percutaneous transluminal coronary angioplasty [32, 33]. Some studies even reported that smokers required less frequent revascularization [9] or had reduced restenosis rates [32, 34, 35], and the existence of a ‘smokers’ paradox’ has been postulated.…”

Section: Discussionmentioning

confidence: 99%

Cigarette Smoke Exposure Promotes Arterial Thrombosis and Vessel Remodeling after Vascular Injury in Apolipoprotein E-Deficient Mice

et al. 2008

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Background: Cigarette smoking is a major risk factor for the development of cardiovascular disease. However, in terms of the vessel wall, the underlying pathomechanisms of cigarette smoking are incompletely understood, partly due to a lack of adequate in vivo models. Methods: Apolipoprotein E-deficient mice were exposed to filtered air (sham) or to cigarette mainstream smoke at a total particulate matter (TPM) concentration of 600 µg/l for 1, 2, 3, or 4 h, for 5 days/week. After exposure for 10 ± 1 weeks, arterial thrombosis and neointima formation at the carotid artery were induced using 10% ferric chloride. Results: Mice exposed to mainstream smoke exhibited shortened time to thrombotic occlusion (p < 0.01) and lower vascular patency rates (p < 0.001). Morphometric and immunohistochemical analysis of neointimal lesions demonstrated that mainstream smoke exposure increased the amount of α-actin-positive smooth muscle cells (p < 0.05) and dose-dependently increased the intima-to-media ratio (p < 0.05). Additional analysis of smooth muscle cellsin vitro suggested that 10 µg TPM/ml increased cell proliferation without affecting viability or apoptosis, whereas higher concentrations (100 and 500 µg TPM/ml) appeared to be cytotoxic. Conclusions: Taken together, these findings suggest that cigarette smoking promotes arterial thrombosis and modulates the size and composition of neointimal lesions after arterial injury in apolipoprotein E-deficient mice.

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Section: Discussionmentioning

confidence: 99%

Cigarette Smoke Exposure Promotes Arterial Thrombosis and Vessel Remodeling after Vascular Injury in Apolipoprotein E-Deficient Mice

et al. 2008

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“…The first nonsurgical drainage procedures were percutaneous, x-raygu ided, pseudocyst punctures with drain placement (15)(16)(17). Ultrasound or computed tomography scan guidance is now routinely used.…”

Section: Discussionmentioning

confidence: 99%

Endoscopic Drainage of Pancreatic Pseudocysts

Liguory

Lefebvre

Vitale

1990

Canadian Journal of Gastroenterology

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Endoscopic drainage of panc reatic pseudocysts was attempted in 17 patients over an eight year period. There were nine cysts located in the head of the pancreas, six in the body and two in the tail. Endoscopic retrograde c holangiopancreatography was performed in all cases and the pancreatic duct satisfactorily opacified in 16 of the 17 patients. This study identified a communication with the pancreatic duct in seven cases. There were two cases in which multiple cysts were present; in each, one cyst was drained endoscopically and the others surgically. Endoscopic drainage of the cyst was immediately possible in 16 of 17 cases (94%). Late follow-up (mean 26 months) documented cyst disappearance in 11 cases (69%). None of the five patients with persistent cysts has required secondary surgical intervention, and the cysts are asymptomatic and stable or decreasing in size by serial scanning. There was one case ( 6%) in which a pseudocyst recurred following initial resolution. There were two complications (12%) requiring surgical intervention: gastrointestinal perforation with peritonitis in one patient and hemorrhage at the cyst margin from an arterial bleeder in another. There were no deaths at 30 days, but in one case a recurrent acute necrotizing pancrearitis occurred 36 days following endoscopic drainage and the patient died. This death was felt to be unrelated to the endoscopic procedure. In conclusion, internal drainage of pancreatic pseudocysts by endoscopic means can be proposed as an alternative to surgical drainage when the cyst can be identified as bulging into the stomach or duodenum. Immediate drainage is usually effective with a minimal lon g term recurrence rate. Can J

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“…Durch die sekundäre Infektion pankreatischer Nekrosen oder Pseudozysten kann sich ein Pankreasabszess ausbilden. In diesem Fall ist eine umgehende Drainage indiziert [47,55,56,57]. Aufgrund der exakten topographischen Darstellung abszesssuspekter pankreatischer Raumforderungen stellt hier die CT-gesteuerte Punktion die Therapie der Wahl dar.…”

Section: Drainage Von Organabszessenunclassified

“…Nach einmaliger Punktion sind pankreatische Abszesse in bis zu 70% rekurrent. Nach Anlage einer PAD kommt es deutlich seltener zum Rezidiv [57,58]. Der technische Erfolg dieser Maßnahme liegt zwischen 70 und 100% [47,55,56,57,59].…”

Section: Drainage Von Organabszessenunclassified

Radiologisch-interventionelle Drainage bei abdomineller Sepsis

Wiggermann

Hunold²

2013

Visc Med

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Hintergrund: Durch sekundäre Infektion pankreatischer Nekrosen und Pseudozysten, putride enterische Infektionen und infolge abdominalchirurgischer Eingriffe kann es zur Ausbildung intraabdomineller Abszesse kommen. Diese stellen Foci septischer Dissemination dar. Die anatomische Lage sowie Ausbreitung lässt sich mittels Computertomographie (CT) exakt bestimmen. Einfache Abszesse sind eindeutig abgrenzbar und treten singulär auf. Komplexe Abszessformationen sind häufig multifokal lokalisiert. Bei Abszessformationen >50 mm ist die Indikation zur radiologisch-interventionellen oder chirurgischen Sanierung zu stellen. Methode: In Abhängigkeit von der topographischen Lage des Abszesses erfolgt der Zugang von ventral, perineal, vaginal oder transgluteal. Abszesspunktion und Drainageanlage werden in Direktpunktions-, Tandem-Trokar- oder Seldinger-Technik vorgenommen. Die Punktion wird unter bildgebender Kontrolle mit Fluoroskopie oder Sukzessivsequenzen durchgeführt. Ergebnisse: Die CT-gesteuerte Anlage einer perkutanen Abszessdrainage (PAD) ist im Fall unkomplizierter und gut zugänglicher intraabdomineller Abszesse die Therapie der Wahl. Eine mögliche Verletzung wichtiger Strukturen auf dem Punktionsweg, wie z.B. von Darm, Milz oder großen Gefäßen, stellt jedoch eine Kontraindikation der PAD dar. Schlussfolgerung: Die PAD ist ein sicheres radiologisch-interventionelles Verfahren. Bei geringerer Krankenhausverweildauer und punktionsbedingter Morbidität ist ihr therapeutischer Erfolg mit jenem der chirurgischen Fokussanierung gleichzusetzen.

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Therapeutic percutaneous aspiration of pancreatic pseudocysts

Cited by 56 publications

References 4 publications

Cigarette Smoke Exposure Promotes Arterial Thrombosis and Vessel Remodeling after Vascular Injury in Apolipoprotein E-Deficient Mice

Cigarette Smoke Exposure Promotes Arterial Thrombosis and Vessel Remodeling after Vascular Injury in Apolipoprotein E-Deficient Mice

Endoscopic Drainage of Pancreatic Pseudocysts

Radiologisch-interventionelle Drainage bei abdomineller Sepsis

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