Therapeutic ultrasound versus sham ultrasound for the management of patients with knee osteoarthritis: a randomized double‐blind controlled clinical study

Ulus, Yasemin; Tander, Berna; Akyol, Yeşim; Durmuş, Dilek; Büyükakincak, Özlem; Gül, Ülkü; Cantürk, Ferhan; Bilgici, Ayhan; Kuru, Ömer

doi:10.1111/j.1756-185x.2012.01709.x

Cited by 50 publications

(50 citation statements)

References 29 publications

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“…However, there are divergences about its efficacy (36). Ulus et al (37) found no significant differences between the use of US and placebo in the VAS scores for patients with knee osteoarthritis. In our study, US reduced pain after therapy; however, effect presented larger size when compared with the use associated with Copaíba oil.…”

Section: Discussionmentioning

confidence: 99%

“…In a previous study (11), US reduced pain and, therefore, increased the mobility of patients with mild knee osteoarthritis. On the other hand, Ulus et al (12) observed that US did not bring more significant improvements to a control group for the variables of pain, physical function, disability and psychological state of patients with knee osteoarthritis. The latest Cochrane database review (13) Patients were randomly divided into three groups: ultrasound group (US); ultrasound group associated with Copaíba oil (US+CO) and a Copaíba oil group (CO).…”

Section: Introductionmentioning

confidence: 99%

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Therapeutic ultrasound associated with copaiba oil reduces pain and improves range of motion in patients with knee osteoarthritis

et al. 2017

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Introduction: Osteoarthritis is a disease that affects millions of Brazilians.Therapeutic ultrasound has been used in its treatment, either alone or associated with drugs. Objective: The aim of this study was to evaluate the effects of ultrasound (US) associated with Copaiba oil (CO) on knee osteoarthritis. Methods: Patients were divided into three different groups: US, US+CO, CO.Ten treatment sessions were held twice a week, 30 minutes each.Pain intensity was assessed through the Visual Analog Scale (VAS) and Range of Motion (ROM) by goniometry, and muscle strength was assessed by means of the Medical Research Council Scale. Statistical analysis was performed by Cohen’s d test, student’s t test and ANOVA, considering p<0.05 as significant. Results: Pain reduced in all groups.The US+CO group (d = -3.50) presented larger effect size when compared to the other groups. Regarding ROM, the largest effect size was observed in the US+CO group for flexion (d = 0.86) and extension (d = 0.97) in comparison with the remainder groups. Muscle strength increased in the US (d = 1.54) and US+CO (d = 1.60) groups for flexion.Regarding extension, the US group presented the largest effect size (d = 1.80). Conclusion: Therapeutic ultrasound associated with copaiba oil is a practical and effective therapy for the treatment of inflammatory diseases such as osteoarthritis.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Therapeutic ultrasound associated with copaiba oil reduces pain and improves range of motion in patients with knee osteoarthritis

et al. 2017

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“…Así, la búsqueda bibliográfica concluyó con 13 ECC [11][12][13][14][15][16][17][18][19][20][21][22][23] (figura 1). La tabla 1 muestra los artículos incluidos en la revisión describiendo el objetivo, la población del estudio, las variables, el análisis y los principales resultados.…”

Section: Bibliográficaunclassified

“…Esto pudo estar influenciado por la falta de poder de este estudio debido a las pérdidas y exclusiones luego de la aleatorización. Ulus et al 18 realizaron 15 sesiones de intervención en un grupo de UST continuo y otro placebo sin encontrar diferencias significativas entre los grupos.…”

Section: Bibliográficaunclassified

“…El UST continuo se genera a través de la excitación constante del transductor con una onda sinusoidal de amplitud constante, produciendo una onda ultrasónica continua del 100% del ciclo de trabajo 25 es decir, que la intensidad y la energía generada por el UST se mantiene constante durante todo el tiempo de aplicación 7 . De los estudios revisados, seis aplicaron UST continuo 14,[15][16][17][18][19] , de los cuales Mascarin et al 15 , Luksurapan et al 16 y Kozanoglu et al 17 reportaron disminución de la intensidad del dolor en el grupo tratado.…”

Section: Parámetros De Aplicación Del Ust En Los Estudios Revisadosunclassified

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Uso del ultrasonido terapéutico pulsado en el tratamiento de personas con osteoartritis de rodilla

Grande

Ramírez

2015

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A Meta‐Analysis of Analgesic Effect of Ultrasound Therapy for Patients With Knee Osteoarthritis

Liu

Wang

et al. 2021

J of Ultrasound Medicine

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To compare the efficacy of therapeutic ultrasound in pain relief and functional recovery in knee osteoarthritis. A comprehensive search of five databases including EMBASE, PubMed, CBM, the Cochrane Library, and Google scholar was conducted to identify relevant studies published between January 1, 2005 and December 31, 2020. Eligible randomized trials were screened for inclusion in this study. Data about the mean change of visual analogue scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and range of motion (ROM) were collected. Fourteen randomized trials covering 1080 patients with treatment durations of 2 to 24 weeks were included. Both pulsed (SMD [CI] = 1.11 [0.86, 1.36], P for heterogeneity < .00001, I2 = 18%) and continuous ultrasound (SMD [CI] = 1.18 [0.78, 1.57], P for heterogeneity < .00001, I2 = 72%) therapy had obvious pain relief effects, and high‐intensity (>1.5 W/cm2) ultrasound seemed more effective (SMD [CI] = 1.34 [0.94, 1.73], P for heterogeneity < .00001, I2 = 35%). In addition, therapeutic ultrasound was also effective in increasing joint function by WOMAC (SMD [CI] = 8.18 [5.88, 10.48], P for heterogeneity < .00001, I2 = 59%). There was a certain degree of heterogeneity due to the differences between the subjects in the study and the ultrasound parameter settings. Our analysis confirmed that both pulsed and continuous ultrasound are effective and safe for pain relief and functional recovery of knee osteoarthritis, especially in high intensity (> 1.5 W/cm2). However, more high‐quality randomized controlled trials will be necessary.

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Therapeutic ultrasound versus sham ultrasound for the management of patients with knee osteoarthritis: a randomized double‐blind controlled clinical study

Abstract: US therapy is safe but use of US in addition to conventional physical therapy programs seems to have no further significant effect in people with knee OA.

Cited by 50 publications

References 29 publications

Therapeutic ultrasound associated with copaiba oil reduces pain and improves range of motion in patients with knee osteoarthritis

Therapeutic ultrasound associated with copaiba oil reduces pain and improves range of motion in patients with knee osteoarthritis

Uso del ultrasonido terapéutico pulsado en el tratamiento de personas con osteoartritis de rodilla

A Meta‐Analysis of Analgesic Effect of Ultrasound Therapy for Patients With Knee Osteoarthritis

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