Therapeutic Use of Immunoglobulins

Stiehm, E. Richard; Ballow, Mark; Lehman, Heather K.

doi:10.1016/j.yapd.2010.08.005

Cited by 29 publications

(24 citation statements)

References 153 publications

(146 reference statements)

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“…Включение в лечебный комплекс ВВИГ G обеспечило восполнение пула иммуноглобулинов в сыворотке крови пациентов, поскольку они удаля-лись при проведении каскадной плазмофильтрации. Способность IgG проникать через гематоэнцефали-ческий барьер, участвовать в интратекальном вос-палении и ремиелинизации, подавлять продукцию аутоантител объясняет необходимость включения данного препарата в комплексную терапию рассеян-ного склероза у детей [19,20]. Частота и спектр вирусов герпеса, которые вы-являлись в сыворотке крови и/или цереброспиналь-ной жидкости, определили необходимость введения в терапию препарата фамцикловир, оказывающего прямое противовирусное действие на вирусы семей-ства Herpesviridae.…”

Section: российский вестник перинатологии и педиатрии 2 2016 Rossiyunclassified

Combination therapy for multiple sclerosis in children

Скрипченко¹,

Ivanova²,

Суровцева³

et al. 2016

Ross. vestn. perinatol. pediatr.

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Section: российский вестник перинатологии и педиатрии 2 2016 Rossiyunclassified

Combination therapy for multiple sclerosis in children

Скрипченко¹,

Ivanova²,

Суровцева³

et al. 2016

Ross. vestn. perinatol. pediatr.

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“…In addition, this procedure reduces the frequency of hospitalizations due to infection, with a consequent reduction of mortality and improving quality of life. 8 The decision to offer GRT should be based on: the patient's diagnosis; proper assessment of serum immunoglobulin levels; other immunological parameters 10 ; and on secondary causes of hypogammaglobulinaemia.…”

Section: Gammaglobulin Replacement Gammaglobulin Replacementmentioning

confidence: 99%

“…The absolute indications for the use of GRT in PID are defects of immunoglobulin production 10 and are represented in Table 3.…”

Section: Gammaglobulin Replacement Gammaglobulin Replacementmentioning

confidence: 99%

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Gammaglobulin for primary immunodeficiency: when should it be used?

Roxo-Junior

2014

Medicina (Ribeirão Preto)

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Antibodies are an essential component of the adaptative immune response and hold long-term memory of the immunological experiences throughout life. Antibody defects represent approximately half of the well-known primary immunodeficiencies requiring gammaglobulin replacement therapy. On the other hand this therapy can be used for some diseases that do not belong to this group, like hyper IgM syndrome, immunodeficiency with thymoma and severe combined immunodeficiency. This therapy is a safe procedure and induces dramatic improvement in the clinical outcome of patients, reducing the risks of death and complications.

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“…Moreover, patients receiving IGIV may have associated risk factors such as diabetes, informahealthcare.com 10.1586/1744666X.2015.1079485 Ó 2015 Informa UK Ltd preexisting renal disease and age differences . Therefore, in IGIV administration, in addition to consider dose of IGIV, patient' weight, infusion rate and interval, the important features affecting clinical tolerability of IGIV such as osmolality, sodium content, sugar content, pH, IgA content and patient risk factors associated should be considered and carefully evaluated for matching them to potential IGIV product risks [11,12].…”

mentioning

confidence: 99%

Different brands of intravenous immunoglobulin for primary immunodeficiencies: how to choose the best option for the patient?

Abolhassani

Asgardoon

Rezaei

et al. 2015

Expert Review of Clinical Immunology

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Immunoglobulin (IG) replacement therapy has served as lifesaving treatment in primary immunodeficiency diseases (PID) for more than six decades. Approximately 70% of patients with PID require IG replacement to maintain their health during the course of disease. It is estimated that about one-third of IG products is used for replacement therapy in these patients. On the other hand, the introduction of newer IG preparations is continuing to improve and extend the quality of life in PID patients. Because of the options available including concentrations, formulations, osmolality, product stabilizers, sodium concentration, anti-infective activity, IgA content and pH, it is important to match the PID patient's complications with potential side effects associated with the composition of a particular IG product. The purpose of this review is to present the clinical differences of intravenous IG among the various preparations regarding PID patients.

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Therapeutic Use of Immunoglobulins

Cited by 29 publications

References 153 publications

Combination therapy for multiple sclerosis in children

Combination therapy for multiple sclerosis in children

Gammaglobulin for primary immunodeficiency: when should it be used?

Different brands of intravenous immunoglobulin for primary immunodeficiencies: how to choose the best option for the patient?

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