Therapy with orally administered methoxsalen and ultraviolet A radiation during childhood increases the risk of basal cell carcinoma

Efficacy and safety of treatments for childhood psoriasis: A systematic literature review

“…120 A relationship between melanoma and UV radiation has been found. 121 In addition, anxiety can be a significant problem in the pediatric group.…”

Basal Cell Carcinomas of the Eyelids

“…The most important environmental risk factor is repeated second-degree solar burns during childhood, the role of the sun exposure depending on the quality and the quantity of melanin of the subject; the most important risk factor is in individuals with a poor pigmented cutaneous phototype [26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45]. …”

“…Other risks factors are therapeutic irradiation with ultraviolet A [45, 46], immunodeficiency [48, 49, 50], chronic arsenic intoxication [51, 52], burn scars [53], and chronic ulcerative scars [54, 55, 56, 57, 58, 59, 60, 61]. …”

Surgical scar remodelling after photodynamic therapy using aminolaevulinic acid or its methylester: a retrospective, blinded study of patients with field cancerization

“…Field cancerization may occur in skin preconditioned by tumorigenic factors, 1–5 producing irreversible cytogenetic changes that induce multifocal cancer growth, 6 especially among those with chronic exposure to ultraviolet radiation. In such patients, surgical excision causes mutilation and scarring due to a large number of tumours and the unremittingly high rate of new tumour creation.…”