Thermal and chemical modification of titanium–aluminum–vanadium implant materials: effects on surface properties, glycoprotein adsorption, and MG63 cell attachment

Dental Implant Surface Enhancement and Osseointegration

“…The extent of material removed depends on the acid concentration, temperature and treatment time. The most commonly used solutions for acid etching of titanium includes either a mixture of HNO 3 and HF or a mixture of HCl and H 2 SO 4 (MacDonald et al, 2004). Acid treatment provides homogeneous roughness, increased active surface area and improved bioadhesion (Braceras et al, 2009).…”

Sol–gel preparation of apatite-coated silica macrospheres from water glass and their adsorption of bovine serum albumin and lysozyme

“…In contrast, the mesopores seemed to disappear due to the HAp-coating, leaving the peak at ³3 nm. Specific surface area (SSA) data were also derived from the N 2 adsorption experiment: 220 and 173 m 2 /g for SiO 2 and HAp-SiO 2 macrospheres, respectively, as listed in Table 1 together with some other properties characteristic of the protein adsorption. Figure 6 shows that BSA and LYZ adsorption on the SiO 2 and HAp-SiO 2 macrospheres was dependent not only on the contact time but also on the protein concentrations of the solutions.…”

“…10)14) Apatite is one of such adsorbents and is employed for chromatographic separation of serum proteins. 15)18) Because of their high tissue compatibility, non-inflammation, and non-immunogenesis, 19) hydroxyapatite [HAp; Ca 10 -(PO 4 ) 6 (OH) 2 ] and ion-substituted non-stoichiometric apatite particles are also employable to remove pathogenic substances. For example, Takashima et al 20) confirmed good blood compatibility of a few non-stoichiometric hydroxyapatite, and showed better adsorption of ¢ 2 -microglobulin (¢ 2 -MG) than that of bovine serum albumin (BSA).…”

“…The original Langmuir equation was derived for gas adsorption under several assumptions. Equation (2) has been sometimes applied to other cases, like the protein adsorption. Rearranging Eq.…”

Osseointegration and Bioscience of Implant Surfaces - Current Concepts at Bone-Implant Interface

“…fibronectin, vitronectin, laminin, serum albumin and collagen) facilitate the attachment of osteogenic cells on titanium surfaces (Park et al, 2005;Yang et al, 2003). Therefore, the protein binding capacity of an implant surface is considered to be an important factor for as successful osseointegration, since surface properties, such as micro-and nano-topography (Lee et al 2010), physicochemical composition (Park et al, 2005) and surface free energy (MacDonald et al, 2004), have an influence on the extend of protein adsorption. It has been documented that osteogenic cells preferably attach to the specific protein sequences, such as the arginine-glycine-aspartic acid (RGD) motif.…”