Thermal Effect of J-Plasma Energy in a Porcine Tissue Model: Implications for Minimally Invasive Surgery

Pedroso, J; Gutierrez, M.; Volker, K.W.

doi:10.1016/j.jmig.2014.08.604

Cited by 13 publications

(21 citation statements)

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“…This allows for effective soft tissue heating and contraction with a relatively shallow depth of the thermal effect. This self‐limiting nature of helium plasma's thermal depth of tissue effect has been demonstrated in several other tissue types and with much higher energy settings than used in this study .…”

Section: Discussionsupporting

confidence: 63%

“…The helium gas plasma soft tissue coagulation device (Bovie J‐Plasma; Bovie Medical Corporation, Clearwater, FL) was evaluated in a commercially available FDA‐approved format with energies selected based on the depth of thermal effects observed for non‐dermatologic tissues at much higher energy levels . Helium plasma energy delivery consisted of single, linear, non‐overlapping passes with continuous energy delivery and 4 L/min helium gas flow at 20% and 40% power levels correlating to energy densities below (8.6 J/cm 2 ) and above (17.8 J/cm 2 ) that used for nitrogen PSR treatment (14.1 J/cm 2 ).…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Helium Plasma Skin Regeneration: Evaluation of Skin Tissue Effects in a Porcine Model and Comparison to Nitrogen Plasma Skin Regeneration

Holcomb¹,

Schucker²

2019

Lasers Surg Med

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Background and Objectives Helium plasma skin regeneration (PSR) is a novel skin rejuvenation technology with significant differences compared with nitrogen PSR technology but that may exert similar skin tissue effects. Study objectives included a comparison of acute and chronic skin tissue changes among the two plasmas in a porcine animal model. Study Design/Materials and Methods In this study, both helium and nitrogen gas plasmas were used to treat the dorsal skin of Yorkshire cross mini pigs with 20% (8.6 J/cm2) and 40% (17.8 J/cm2) power helium plasma single pass treatment (4 liter gas flow, continuous energy delivery, and linear non‐overlapping passes) compared with high energy nitrogen plasma double pass treatment (PSR3 @ 14.1 J/cm2: 4.0 J, 2.5 Hz pulse rate, overlapping horizontal, and vertical passes). Acute and chronic skin contraction, maximum acute depth of injury and chronic reparative healing depth were assessed along with representative histopathology in each treatment paradigm. Results High‐energy nitrogen plasma treatment exhibited greatest mean depth of acute tissue injury 4 hours post‐treatment whereas helium plasma treatment exhibited greater acute skin tissue contraction. Then, 20% and 40% power helium plasma treatment results were each very similar among animals as a percentage of nitrogen plasma treatment results for both depths of acute tissue injury and acute skin tissue contraction. Mean depths of reparative tissue healing were similar among treatment paradigms 30 days after treatment with significant intra‐ and inter‐animal variability observed within each treatment paradigm. Thirty‐day mean skin tissue contraction was greater for helium plasma treatment; however, the data varied significantly between animals in all paradigms. Histopathologic tissue evaluation after 30 days showed similar findings among the treatment paradigms with epidermal hyperplasia, flattening of rete ridges and with regenerative granulation tissue expanding the superficial and papillary dermis. Conclusions This study demonstrates modestly reduced depth of the thermal effect, greater skin tissue contraction and similarity of acute and chronic histopathological findings for helium plasma when compared with nitrogen plasma in a porcine animal model. © 2019 The Authors. Lasers in Surgery and Medicine published by Wiley Periodicals, Inc.

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Section: Discussionsupporting

confidence: 63%

Section: Methodsmentioning

confidence: 99%

Helium Plasma Skin Regeneration: Evaluation of Skin Tissue Effects in a Porcine Model and Comparison to Nitrogen Plasma Skin Regeneration

Holcomb¹,

Schucker²

2019

Lasers Surg Med

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“…18 This mechanism is similar to the mechanism of surgical hemostats that stimulate aggregation of platelets and coagulation factors. 19 In a study by Pedroso et al, 20 this specific device was applied on porcine liver, kidney, and muscle tissue at different power levels and gas flows. It was shown that J-Plasma has minimal lateral and depth spread when it is applied to various tissue types, even at higher power settings or gas flow rates.…”

Section: Discussionmentioning

confidence: 99%

Utilization of low-temperature helium plasma (J-Plasma) for dissection and hemostasis during carotid endarterectomy

Filis

Galyfos

Sigala

et al. 2020

Journal of Vascular Surgery Cases, Innovations and Techniques

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Herein we report nine cases of carotid endarterectomy in which we used a cold atmospheric helium plasma device (J-Plasma; Apyx Medical Corporation, Clearwater, Fla). Although clinical reports are limited, experimental data indicate that this technology could be used for dissection and coagulation during surgery, yielding limited adjacent tissue damage. As a result, it could be extremely useful in procedures like carotid endarterectomy that necessitate careful dissection and coagulation with limited damage of adjacent neurovascular structures. (J Vasc Surg Cases and Innovative Techniques 2020;6:152-5.)

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“…It has been used in different fields (from general to gynecology surgery) for open and laparoscopic cases. 1 In plastic/cosmetic surgery, radio frequency helium plasma has been shown to be very effective for skin rejuvenation and skin tightening and also for rhinophyma reduction and skin cancer treatment. 2 …”

Section: Dear Sirmentioning

confidence: 99%

The Use of Cold Atmospheric Plasma Device in Flap Elevation

Pinelli

Starnoni

Santis

2020

Plastic and Reconstructive Surgery - Global Open

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Thermal Effect of J-Plasma Energy in a Porcine Tissue Model: Implications for Minimally Invasive Surgery

Cited by 13 publications

References 0 publications

Helium Plasma Skin Regeneration: Evaluation of Skin Tissue Effects in a Porcine Model and Comparison to Nitrogen Plasma Skin Regeneration

Helium Plasma Skin Regeneration: Evaluation of Skin Tissue Effects in a Porcine Model and Comparison to Nitrogen Plasma Skin Regeneration

Utilization of low-temperature helium plasma (J-Plasma) for dissection and hemostasis during carotid endarterectomy

The Use of Cold Atmospheric Plasma Device in Flap Elevation

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