The feasibility of a solar-ORC system for domestic combined heat and power generation (CHP) is deeply affected by both the time-varying ambient conditions (e.g. solar irradiance, temperature, wind speed) and the thermal and electrical load profiles variability of the final application. The definition of a proper control strategy is proven to be a major design-challenge for successful operation of solar-ORC systems, with the main goal of assuring that the thermal power demand for space heating and Domestic Hot Water (DHW) production and the electricity needs are simultaneously satisfied. The rising demand for energy-autonomous systems also calls for the inclusion of a storage system within the base-layout, that could assure the electricity demand is properly matched after sunset or in very-low irradiance conditions, such as cloudy days. A comprehensive model accounts for the dynamic of the plant-integrated unit, featuring an ORC-based plant that bottoms a flat plate solar thermal collector: a parametric study is presented, and an off-design analysis is performed to properly assess the energy performance of the system. The heat availability to the ORC heat exchanger is evaluated, based on solar availability, thermal losses in the pipes and plant requirements, in terms of operating temperature and pressures and organic fluid mass flowrate. R245fa is selected as working fluid in the ORC-section. Sliding vanes machines expander and pump – are considered as rotary equipment. Flat plate heat exchangers complete the base layout, the analysis accounts for. Due to the need for DHW production, a storage unit for hot water is present, upstream the recovery branch: dependently on the ability the fluid at the collector outlet has to meet the ORC requirements for proper operation (about 110°C), the ORC evaporator is fed and the recovery section enabled. Both continuous and unsteady operation underwent an in-depth analysis, as well as the benefits associated with different discharge times for the storage unit. A dedicated control strategy is defined, dependently on whether the electrical output or the thermal one need to be maximized, and accounts for either a flash or a progressive tank discharge. A virtual platform allowed the setting-up of a pilot plant, for direct performance assessment, in presence of different amounts of tank discharges per day and different lower temperatures at the storage tank.