“…(1) Various researchers (Atherton and Thorpe, 1980;Barrett et al, 2004;Brown, 2000;Montville and Sapers, 1981;Nelson and Tressler, 1980;Stumbo et al, 1975) and trade associations (Institut-Appert, 1979;National Canners Association Research Laboratories, 1968;NFPA, 1971NFPA, , 1982NFPA, , 1985 have provided guidelines on minimal lethality requirements for the thermal processing of canned foods. In general, for low-acid foods, a minimum F o = 3 min (to achieve book-cook or 12-D reduction of Clostridium botulinum spores) is necessary; although, conservatively, a higher lethality between 5-15 min is usually applied.…”