Thermoregulatory effects of intracranial norepinephrine injections in goldfish

Wollmuth, Lonnie P.; Crawshaw, Larry I.; Panayiotides-Djaferis, Hercules Theodore

doi:10.1152/ajpregu.1987.253.6.r821

Cited by 7 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The preoptic nucleus is involved in maintenance of temperature in teleosts as in other ectothermic and endothermic vertebrates [Nelson et al, 1984], and it has been dem onstrated that injections of norepinephrine into the anterior aspect of the nucleus preopticus periventricularis [terminology of Peter and Gill, 1975, i.e. the nu cleus preopticus parvocellularis anterioris of Braford and Northcutt, 1983] leads to a decrease in the tem perature preference of fish in a thermal gradient [Wollmuth et al, 1987], Effective injections were located within the region of the parvocellular preoptic nucleus where presumptive norepinephrine in nervation is moderately dense, and this suggests that norepinephrine plays a role in thermoregulation in teleosts.…”

Section: Th-and Dbh-ir Fibers and Terminalsmentioning

confidence: 99%

Distribution of Catecholamine-Synthesizing Enzymes in Goldfish Brains: Presumptive Dopamine and Norepinephrine Neuronal Organization

Hornby

Piekut²

1990

Brain Behav Evol

View full text Add to dashboard Cite

The organization of presumptive dopamine- and norepinephrine-synthesizing neurons in the brains of goldfish is described by using antibodies to tyrosine hydroxylase (TH) and dopamine β-hydroxylase (DBH) with avidin-biotin immunocytochemical techniques. In the hindbrain, TH-immunoreactive (IR) and DBH-IR cell bodies are located together in the following three regions: (1) dorsomedial medulla in the post-obecular region, (2) medullary tegmentum from the level of the greatest expansion of the vagal lobes to the medullospinal transition, and (3) isthmal tegmentum dorsolateral to the medial longitudinal fasciculus. Elsewhere in the brain, TH-IR neurons were visualized in eight distinct forebrain neuronal groups; DBH-IR cell bodies were not observed. Fibers and terminals IR for TH and DBH were most dense in forebrain periventricular regions, i.e. adjacent to the third ventricle, and specifically around the lateral and preoptic recesses. In the telencephalon, a dense innervation of TH- and DBH-IR fibers was noted within the area dorsalis, pars lateralis and pars dorsalis. Within the area dorsalis, pars centralis TH-IR fibers were dense; DBH-IR fibers were not visualized in this region. The presence of both dopamine- and norepinephrine-synthesizing neurons in the isthmal and medullary tegmentum and in the dorsomedial medulla provides evidence indicating that these regions are homologous to the locus ceruleus, medullary reticular nucleus and area postrema, respectively, in tetrapod brains. In addition, the remarkably dense innervation of TH-IR and DBH-IR fibers and terminals in periventricular regions of the hypothalamus and within the telencephalon suggests that there are potential similarities in the catecholaminergic innervation of forebrain regions of teleost and mammalian brains.

show abstract

Section: Th-and Dbh-ir Fibers and Terminalsmentioning

confidence: 99%

Distribution of Catecholamine-Synthesizing Enzymes in Goldfish Brains: Presumptive Dopamine and Norepinephrine Neuronal Organization

Hornby

Piekut²

1990

Brain Behav Evol

View full text Add to dashboard Cite

show abstract

“…Intrahypothalamic injections of both norepinephrine and dopamine elicit the selection of lower temperatures in goldfish (35,36). Both ␣ 1 and ␣ 2 adrenoceptors, but not ␤ receptors, are involved in the anapyrexic response to norepinephrine (37).…”

Section: Discussionmentioning

confidence: 99%

“…A guide cannula with a Teflon-coated silver reference electrode mounted on its outer wall was implanted in each fish following previously described stereotaxic procedures (36). A small puncture through the meninges allowed the tip of the guide cannula to be placed in contact with the caudal portion of the tectum.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Effects of hypoxia, anoxia, and endogenous ethanol on thermoregulation in goldfish,Carassius auratus

Rausch

Crawshaw

Wallace

2000

American Journal of Physiology-Regulatory, Integrative and Comp

View full text Add to dashboard Cite

Effects of hypoxia, anoxia, and endogenous ethanol (EtOH) on selected temperature (T(sel)) and activity in goldfish were evaluated. Blood and brain EtOH concentrations ([EtOH]) and brain oxygen partial pressure (PO(2)) were quantified at crucial ambient oxygen pressures. Below a threshold value near 31 Torr, T(sel) decreased as a function of environmental PO(2). T(sel) of 15 degrees C-acclimated fish was approximately 10 degrees C at the onset of anoxia and changed little over 2 h. Activity showed a similar response pattern. Brain [EtOH] was significantly elevated above control levels after 1 h anoxia. In normoxic water, T(sel) remained different in previously anoxic and normoxic control fish for approximately 20 min. Blood [EtOH] of previously anoxic fish remained significantly elevated ([EtOH] >4.0 micromol/g blood), and activity was significantly depressed at 20 min. Brain PO(2) reached normal levels in <3 min. We conclude that [EtOH] (brain or blood) and brain PO(2) are not proximal causes of either behavioral anapyrexia (hypothermia) or inactivity in goldfish exposed to oxygen-depleted environments.

show abstract

“…Moreover, cholinergic stimulation lowers escape temperatures, whereas an increased level of catecholamine raises them (Green and Lomax, 1976). 5‐HT and NE increases the selected temperature in fish (Gryer and Ogilvie, 1978; Wollmuth et al, 1987, 1988). These evidences indicate that the neurotransmitters are involved in the temperature selection of fish.…”

Section: Introductionmentioning

confidence: 99%

Heat stress induced histopathology and pathophysiology of the central nervous system

Ahmed

2005

Intl J of Devlp Neuroscience

View full text Add to dashboard Cite

The number of reports on the effects of heat stress is still increasing on account of the temperature is one of the most encountered stressful factors on the different biological systems. Because the heat stress (HS) considered a model of thermal injury to the central nervous system (CNS), the purpose of this review was to assess the histopathological changes of HS on CNS. Also, this review emphasized that the heat stress may retard partially the degree of the postnatal neurogenesis and growth of CNS. Taken together, owing to one of the most important functions of heat shock protein is to protect the organisms from the deleterious effects of temperature, thus, it can be hypothesized that the formation of heat shock proteins may be related to the deleterious effect of HS. On the other hands, the alterations of neurotransmitters in the central nervous system might be involved in the physiological and biochemical responses that occur during heat stress. The hypothalamic monoaminergic systems play an important role in the thermoregulation through regulate the heat production and heat dissipation. In addition, the disturbance in the biochemical variables due to the high temperature may be the cause of the histopathological changes and the partial retardation in CNS and the reverse is true. Thus, further studies need to be done to emphasize this concept.

show abstract

Thermoregulatory effects of intracranial norepinephrine injections in goldfish

Cited by 7 publications

References 0 publications

Distribution of Catecholamine-Synthesizing Enzymes in Goldfish Brains: Presumptive Dopamine and Norepinephrine Neuronal Organization

Distribution of Catecholamine-Synthesizing Enzymes in Goldfish Brains: Presumptive Dopamine and Norepinephrine Neuronal Organization

Effects of hypoxia, anoxia, and endogenous ethanol on thermoregulation in goldfish,Carassius auratus

Heat stress induced histopathology and pathophysiology of the central nervous system

Contact Info

Product

Resources

About