Thermoresponsive magnetic nanoparticle – Aminated guar gum hydrogel system for sustained release of doxorubicin hydrochloride

Murali, Ragothaman; Vidhya, P; Thanikaivelan, P.

doi:10.1016/j.carbpol.2014.04.076

Cited by 73 publications

(27 citation statements)

References 30 publications

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“…The other signals in the spectrum correspond to the vibrations arising from the amorphous phase of the polymer. These results are in good agreement with the FTIR signal characteristics already described in the literature for PGG and PVDF [32,33,41].…”

Section: Resultssupporting

confidence: 92%

“…It is basically composed of a straight chain backbone of D-mannose units, united by β (1-4) glycoside linkages, and bears a single Dgalactose side chain unit on approximately every alternate mannose, joined to it by an α (1-6) glycoside linkage (see Fig. 1) [32,33] making it an attractive system for exploring as a binder for LIBs as indicated in the present study. In recent publication, gaur gum and its derivative has been reported as a suitable binder for silicon nanoparticles which shows excellent electrochemical performance [34,35].…”

Section: Introductionmentioning

confidence: 99%

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Guar gum: Structural and electrochemical characterization of natural polymer based binder for silicon–carbon composite rechargeable Li-ion battery anodes

Kuruba

Datta

Damodaran

et al. 2015

Journal of Power Sources

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Long term cyclability of a composite Li-ion anode electrode comprised of 82 wt.% Si/C lithium ion active material along with 8 wt.% polymeric binder and 10 wt.% Super P conductive carbon black has been studied utilizing polymeric binders exhibiting different elastic/tensile moduli and tensile yield strengths. Accordingly electrochemically active Si/C composite synthesized by high energy mechanical milling (HEMM), exhibiting reversible specific capacities of ~780mAh/g and ~600mAh/g at charge/discharge rates of ~50mA/g and ~200mA/g, respectively were selected as the Li-ion active anode. Polyvinylidene fluoride (PVDF) and purified guar gum (PGG) with reported elastic modulus ~1000MPa and ~3200MPa, respectively were selected as the binders.Results show that the composite electrode (Si/C + binder + conducting carbon) comprising the higher elastic modulus binder (PGG) exhibits better long term cyclability contrasted with PVDF. 1 H NMR analysis of the polymer before and after cycling shows structural degradation/deformation of the low elastic modulus PVDF, whereas the high elastic modulus PGG binder shows no permanent structural deformation or damage. The results presented thus suggest that PGG based polymers exhibiting high elastic modulus are a promising class of binders with the desired mechanical integrity needed for enduring the colossal volume expansion stresses of Si/C based composite anodes.

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Section: Resultssupporting

confidence: 92%

Section: Introductionmentioning

confidence: 99%

Guar gum: Structural and electrochemical characterization of natural polymer based binder for silicon–carbon composite rechargeable Li-ion battery anodes

Kuruba

Datta

Damodaran

et al. 2015

Journal of Power Sources

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“…In past decades, thermoresponsive magnetic microspheres have emerged as a great potential technology platform for targeted and controlled drug delivery . First, magnetic components can guide microspheres to lesions directly by an external magnetic field and release drug at the right place.…”

Section: Introductionmentioning

confidence: 99%

Thermoresponsive hollow magnetic microspheres with hyperthermia and controlled release properties

Chen

Zhang

et al. 2015

J of Applied Polymer Sci

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Thermoresponsive hollow magnetic microspheres consisting of a hollow magnetic core, a carbon shell, and a smart polymer layer are presented in this article. A carbon nanomaterial was used as a steric stabilizer for Fe 3 O 4 nanoparticles and a supporter for polymer. The thermoresponsive monomer, N-isopropyl acrylamide, was grafted on the carbon-encapsulate hollows by surface radical polymerization. The experimental results indicate that the composites had a phase-transition temperature around 438C and a saturation magnetization of 56.9 emu/g; this showed apparent thermosensitivity and magnetism. The performances in hyperthermia evaluated by an inductive magnetic field showed that the hybrid microspheres had a specific absorption rate of 240 W/g. The model drug, 5-fluorouracil, was loaded in and released from the microspheres with different release rates at 35 and 508C. This demonstrated that the as-synthesized microspheres had a thermotriggered release ability and would be a good drug carrier in the biomedical field.

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“…[53][54][55] Biodistribution study. But different system may behave differently, possibly dependent on how much drug will finally transport into blood circulation.…”

Section: Anti-tumor Studies Of Dox/tio 2 @Mwcnts/pegda In Vivomentioning

confidence: 99%

Near-infrared-triggered in situ hybrid hydrogel system for synergistic cancer therapy

Zhang

Zhu

et al. 2015

J. Mater. Chem. B

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Thermoresponsive magnetic nanoparticle – Aminated guar gum hydrogel system for sustained release of doxorubicin hydrochloride

Cited by 73 publications

References 30 publications

Guar gum: Structural and electrochemical characterization of natural polymer based binder for silicon–carbon composite rechargeable Li-ion battery anodes

Guar gum: Structural and electrochemical characterization of natural polymer based binder for silicon–carbon composite rechargeable Li-ion battery anodes

Thermoresponsive hollow magnetic microspheres with hyperthermia and controlled release properties

Near-infrared-triggered in situ hybrid hydrogel system for synergistic cancer therapy

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