2010
DOI: 10.1523/jneurosci.3860-09.2010
|View full text |Cite
|
Sign up to set email alerts
|

Theta-Band Phase Locking of Orbitofrontal Neurons during Reward Expectancy

Abstract: The expectancy of a rewarding outcome following actions and cues is coded by a network of brain structures including the orbitofrontal cortex. Thus far, predicted reward was considered to be coded by time-averaged spike rates of neurons. However, besides firing rate, the precise timing of action potentials in relation to ongoing oscillations in local field potentials is thought to be of importance for effective communication between brain areas.We performed multineuron and field potential recordings in orbitof… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

7
84
1
1

Year Published

2011
2011
2021
2021

Publication Types

Select...
9

Relationship

1
8

Authors

Journals

citations
Cited by 98 publications
(93 citation statements)
references
References 59 publications
7
84
1
1
Order By: Relevance
“…Selection of hippocampal inputs along these lines could accomplish the association of place and reward thought to underlie place preference and directed movement initiation (Pennartz et al, 1994;Ito et al, 2008). Of course, such a mechanism would not preclude interactions with other inputs converging on the ventral striatum, such as those from prefrontal cortical areas (where theta rhythms and phase locking are also prominent) (Jones and Wilson 2005a,b;Siapas et al, 2005;Hyman et al, 2010;van Wingerden et al, 2010).…”
Section: Discussionmentioning
confidence: 99%
“…Selection of hippocampal inputs along these lines could accomplish the association of place and reward thought to underlie place preference and directed movement initiation (Pennartz et al, 1994;Ito et al, 2008). Of course, such a mechanism would not preclude interactions with other inputs converging on the ventral striatum, such as those from prefrontal cortical areas (where theta rhythms and phase locking are also prominent) (Jones and Wilson 2005a,b;Siapas et al, 2005;Hyman et al, 2010;van Wingerden et al, 2010).…”
Section: Discussionmentioning
confidence: 99%
“…Therefore, the use of high QHCl concentrations is not an ideal stimulus to uncover pure taste coding mechanisms, since it will not only induce an aversive (bitter) taste sensation, but will also activate neural pathways that reduce consummatory licking and induce an overall state of fear [or punishment (41)]. If a suprathreshold QHCl concentration is to be used, then attention must be paid to control for different oromotor responses (24) evoked by QHCl vs. other tastants (e.g., sucrose) before attributing that neuronal changes are driven only by reward and punishment mechanisms, instead of oromotor differences (31,35,50).…”
Section: Discussionmentioning
confidence: 99%
“…Although we focused on ventral striatum here because of the availability of phase precession data from that structure, it is probable that many brain regions represent future events as part of a circuit involving frontal cortex and basal ganglia, as well as the hippocampus and striatum [46][47][48][49][50][51][52]. There is evidence that theta-like oscillations coordinates the activity in many of these brain regions [53][54][55][56]. For instance, 4 Hz oscillations show phase coherence between the hippocampus, prefrontal cortex and ventral tegmental area (VTA), a region that signals the presence of unexpected rewards [56].…”
Section: Neural Representation Of Predictionsmentioning
confidence: 99%