Theta oscillation in the human anterior cingulate cortex during all-night sleep: an electrocorticographic study

Nishida, Masaki; Hirai, Nobuhide; Miwakeichi, Fumikazu; Maehara, Taketoshi; Kawai, Kensuke; Shimizu, Hiroyuki; Uchida, Sunao

doi:10.1016/j.neures.2004.08.004

Cited by 45 publications

(32 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although in human REM sleep a pronounced spectral peak of theta power within the surface EEG is typically absent, anterior cortical theta generators and enhanced frontal theta activity have been discerned [18], [19], [28]. The present enhancement of broadband gamma EEG activity by theta-tDCS indicates that theta-tDCS was indeed effective, apparently boosting a rhythm inherent to the present state, but not maximally expressed at the time of stimulation.…”

Section: Discussionmentioning

confidence: 59%

Transcranial Electrical Currents to Probe EEG Brain Rhythms and Memory Consolidation during Sleep in Humans

et al. 2011

View full text Add to dashboard Cite

Previously the application of a weak electric anodal current oscillating with a frequency of the sleep slow oscillation (∼0.75 Hz) during non-rapid eye movement sleep (NonREM) sleep boosted endogenous slow oscillation activity and enhanced sleep-associated memory consolidation. The slow oscillations occurring during NonREM sleep and theta oscillations present during REM sleep have been considered of critical relevance for memory formation. Here transcranial direct current stimulation (tDCS) oscillating at 5 Hz, i.e., within the theta frequency range (theta-tDCS) is applied during NonREM and REM sleep. Theta-tDCS during NonREM sleep produced a global decrease in slow oscillatory activity conjoint with a local reduction of frontal slow EEG spindle power (8–12 Hz) and a decrement in consolidation of declarative memory, underlining the relevance of these cortical oscillations for sleep-dependent memory consolidation. In contrast, during REM sleep theta-tDCS appears to increase global gamma (25–45 Hz) activity, indicating a clear brain state-dependency of theta-tDCS. More generally, results demonstrate the suitability of oscillating-tDCS as a tool to analyze functions of endogenous EEG rhythms and underlying endogenous electric fields as well as the interactions between EEG rhythms of different frequencies.

show abstract

Section: Discussionmentioning

confidence: 59%

Transcranial Electrical Currents to Probe EEG Brain Rhythms and Memory Consolidation during Sleep in Humans

et al. 2011

View full text Add to dashboard Cite

show abstract

“…As in several of our subjects, a negative correlation was found over the inferior frontal cortex, middle temporal gyrus, inferior parietal lobule, precuneus and posterior cingulate cortex. In our study, we potentially recorded and analyzed different types of theta rhythms (during wakefulness and during light sleep) characterized by different generators (Cantero et al, 2003;Nishida et al, 2004). However, in our condition of recording, without specific cognitive task, the theta rhythm specifically related to light sleep was more likely to be predominant.…”

Section: Cerebral Correlates Of Thetamentioning

confidence: 94%

Effects of fluctuating physiological rhythms during prolonged EEG-fMRI studies

Tyvaert¹,

LeVan²,

Grova³

et al. 2008

Clinical Neurophysiology

View full text Add to dashboard Cite

Objective-We evaluated BOLD correlates of alertness fluctuations commonly seen during prolonged EEG-fMRI studies to better define the brain areas active at different phases of vigilance and to assess the contribution of these fluctuations to the BOLD signal.Methods-We evaluated BOLD changes specifically related to the main physiological EEG rhythms (alpha, beta, theta, delta, spindles) in 15 epilepsy patients with rare discharges (all the regressors were included in the same general linear model to improve specificity).Results-We found a consistent effect of spindles, alpha and theta. For alpha, BOLD was positively correlated in thalami and putamen, and negatively correlated in the occipital, parietal and frontal lobes. For theta, a negative correlation was found over the parietal, temporal and frontal lobes. Spindles were correlated with a positive BOLD in thalami and putamen. Rhythm regressors added as confounds in the fMRI analysis explained at least 5% of BOLD signal variance in 6.8 ± 8.9% of gray matter voxels, a contribution which is of the order of typical changes in fMRI studies.Conclusion-First, we found specific cerebral structures involved in each main EEG rhythm generation. Second, fluctuations of these rhythms following vigilance changes are responsible for noteworthy BOLD changes. Significance: Physiological EEG rhythms may be integrated to the analysis of EEG-fMRI in studies with fluctuation of alertness, to eliminate possible confounding factors.

show abstract

“…In humans, EEG theta activity during REM sleep is less coherent and persistent in hippocampal regions and is seen as well in neocortical areas, again also during wakefulness (174,860,1222,1223). Theta activity in waking is considered a condition favoring the encoding of new information and associated synaptic plastic processes in hippocampal networks (64, 371,612,1251).…”

Section: Theta Activitymentioning

confidence: 99%

About Sleep's Role in Memory

Rasch

Born

2013

Physiological Reviews

2,274

2,026

View full text Add to dashboard Cite

Over more than a century of research has established the fact that sleep benefits the retention of memory. In this review we aim to comprehensively cover the field of "sleep and memory" research by providing a historical perspective on concepts and a discussion of more recent key findings. Whereas initial theories posed a passive role for sleep enhancing memories by protecting them from interfering stimuli, current theories highlight an active role for sleep in which memories undergo a process of system consolidation during sleep. Whereas older research concentrated on the role of rapid-eye-movement (REM) sleep, recent work has revealed the importance of slow-wave sleep (SWS) for memory consolidation and also enlightened some of the underlying electrophysiological, neurochemical, and genetic mechanisms, as well as developmental aspects in these processes. Specifically, newer findings characterize sleep as a brain state optimizing memory consolidation, in opposition to the waking brain being optimized for encoding of memories. Consolidation originates from reactivation of recently encoded neuronal memory representations, which occur during SWS and transform respective representations for integration into long-term memory. Ensuing REM sleep may stabilize transformed memories. While elaborated with respect to hippocampus-dependent memories, the concept of an active redistribution of memory representations from networks serving as temporary store into long-term stores might hold also for non-hippocampus-dependent memory, and even for nonneuronal, i.e., immunological memories, giving rise to the idea that the offline consolidation of memory during sleep represents a principle of long-term memory formation established in quite different physiological systems.

show abstract

Theta oscillation in the human anterior cingulate cortex during all-night sleep: an electrocorticographic study

Cited by 45 publications

References 51 publications

Transcranial Electrical Currents to Probe EEG Brain Rhythms and Memory Consolidation during Sleep in Humans

Transcranial Electrical Currents to Probe EEG Brain Rhythms and Memory Consolidation during Sleep in Humans

Effects of fluctuating physiological rhythms during prolonged EEG-fMRI studies

About Sleep's Role in Memory

Contact Info

Product

Resources

About