Thio Arsenosugars Identified as Natural Constituents of Mussels by Liquid Chromatography‐Mass Spectrometry.

Abstract

Carbohydrates U 0500Thio Arsenosugars Identified as Natural Constituents of Mussels by Liquid Chromatography-Mass Spectrometry. -Two novel thio arsenosugars (II) are identified by LC-MS coupling and independent synthesis from the corresponding arsine oxides (I). -(SCHMEISSER, E.; RAML, R.; FRANCESCONI*, K. A.; KUEHNELT, D.; LINDBERG, A.-L.; SOEROES, C.; GOESSLER, W.; Chem.

Overview of hyphenated techniques using an ICP-MS detector with an emphasis on extraction techniques for measurement of metalloids by HPLC–ICPMS

“…However, there are at least 40 minor arsenic species [58]. Recently two new classes of arsenic species, the thioarsenic species where the 'O' bonded to As is replaced by an "S" and arsenic lipids (arsenic hydrocarbons and arsenophospholipids) have been discovered increasing the complexity of arsenic species that exist in marine organisms [59].…”

Arsenic speciation in food chains from mid-Atlantic hydrothermal vents

“…This procedure oxidized thio-arsenosugars to oxo-arsenosugars, allowing quantification of the thio-arsenosugars by difference. [36] Oxidation of As(III) to As(V) occurrs simultaneously by this method.Reverse phase chromatography using a Shisheido Capcell PAK C18 MGII (4.6 mm × 250 mm, 5 μm, Shiseido Co., Ltd., Tokyo, Japan) with a mobile phase of 10 mM sodium 1-butansulfonate, 4 mM tetramethylammonium hydroxide, 4 mM malonic acid, 0.5% methanol at pH 3, with a flow rate of 1.0 mL min −1 [37] was used for separation of co-eluting unknown organic arsenic species.…”

“…This procedure oxidized thio-arsenosugars to oxo-arsenosugars, allowing quantification of the thio-arsenosugars by difference. [36] Oxidation of As(III) to As(V) occurrs simultaneously by this method.…”

“…Rather, we found that thio-arsenosugar-PO 4 , analyzed in a subset of samples, comprised 14–31% of extractable As in three of the mussel samples, but was absent from one mussel sample and two polychaete samples. The absence of the thio-arsenosugar-PO 4 in some samples may be due oxidation in the freeze-dried sample during storage, [36, 47] or in the sample extracts which were stored up to 4 days prior to analysis. The potential oxidation of thio-arsenosugars during storage makes precise quantitation of this As species problematic, however, the formation of thio-arsenosugars during storage has been shown to be unlikely, [48] confirming the observed presence of this species is not an artifact.…”

Microbial transformation of arsenic species in municipal landfill leachate

“…Recently, thiol-organoarsenic species, including DMDTA V and DMMTA V , have been reported in a wide range of systems, such as in marine algae [13], vegetation [14], mussels [15], animals [2,[16][17][18][19], and human beings [20,21]. Ochi et al [4] and Naranmandura et al [22] suggested that biologically generated sulfide (HS − ), glutathione (GSH), or sulfide coordinated with a monothiol (protein-S-SH) or dithiol group (protein-S-S-S-protein) may be involved in biological arsenic transformation.…”