Thiochromenes and hydrothiochromenes (review)

Klimenko, S. K.; Харченко, В. Г.; Stolbova, T. V.

doi:10.1007/bf00635932

Cited by 3 publications

(1 citation statement)

References 40 publications

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“…2 H -1-Benzothiopyrans 1 , commonly known as thiochromenes, are an important heterocyclic class of compounds found in a number of pharmaceutical agents − including anticancer, , anticonvulsant, anti-HIV, and antibacterial agents . Owing to their pharmacological importance, a number of synthetic protocols have been reported for the synthesis of thiochromenes. − However, there have been very few literature reports on stereoselective synthetic approaches to such compounds.…”

Section: Introductionmentioning

confidence: 99%

Stereoselective Synthesis of Thiochromenes via Intramolecular Tandem Thio-Michael Addition of in Situ Generated α,β-Unsaturated Aldehydes

et al. 2014

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An efficient and highly stereoselective strategy for the synthesis of 2,3-substituted thiochromenes having a complex and easily transformable group at the stereogenic center has been developed via a tandem thio-Michael addition reaction of an in situ generated α,β-unsaturated aldehyde sugar derivative. The protocol is superior to reported protocols in that the carbohydrate-derived substituent at the stereogenic center of the thiochromene is versatile and is amenable for further transformation.

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Section: Introductionmentioning

confidence: 99%

Stereoselective Synthesis of Thiochromenes via Intramolecular Tandem Thio-Michael Addition of in Situ Generated α,β-Unsaturated Aldehydes

et al. 2014

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Organometallic Complexes of Pyridines and Benzannulated Pyridines

Sadimenko

2004

Advances in Heterocyclic Chemistry

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Thiocoumarins and Dithiocoumarins: Advances in Synthesis and Pharmacological Activity

Chaudhary

Pramanik

Santra

2020

COC

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: Thiocoumarins and dithiocoumarins are two important classes of sulfur containing heterocyclic compounds which are bioisosteres of coumarins. Herein, various literature reported synthetic strategies for these two classes of heterocylic compounds have been discussed. Different solvents, catalysts, reagents and reaction conditions which were employed successfully for synthesizing thiocoumarins and dithiocoumarins have also been described concisely in this review. Mechanistic discussion has been done wherever it was necessary. In addition, a comparative view of various solvents, catalysts and reagents toward their efficiency for synthesizing thiocoumarins and dithiocoumarins, have been discussed as well. Furthermore, pharmacological activities of these two classes of compounds have also been discussed.

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Thiochromenes and hydrothiochromenes (review)

Cited by 3 publications

References 40 publications

Stereoselective Synthesis of Thiochromenes via Intramolecular Tandem Thio-Michael Addition of in Situ Generated α,β-Unsaturated Aldehydes

Stereoselective Synthesis of Thiochromenes via Intramolecular Tandem Thio-Michael Addition of in Situ Generated α,β-Unsaturated Aldehydes

Organometallic Complexes of Pyridines and Benzannulated Pyridines

Thiocoumarins and Dithiocoumarins: Advances in Synthesis and Pharmacological Activity

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