2004
DOI: 10.1148/radiol.2313030347
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Thoracic Tumors Treated with CT-guided Radiofrequency Ablation: Initial Experience

Abstract: RF ablation seems to be a promising treatment for malignant thoracic tumors.

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Cited by 200 publications
(114 citation statements)
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“…Histopathological examination of post 3 months tru cut biopsy was comparable to Yasui et al, [26] who reported that histopathological findings after 2 months were necrosis, fibrosis, or both, with no viable cells in 20 of 33 (60.6%) ablation zones, and residual tumor cells in 13(39.4%) ablation zones.…”
Section: Discussionsupporting
confidence: 75%
“…Histopathological examination of post 3 months tru cut biopsy was comparable to Yasui et al, [26] who reported that histopathological findings after 2 months were necrosis, fibrosis, or both, with no viable cells in 20 of 33 (60.6%) ablation zones, and residual tumor cells in 13(39.4%) ablation zones.…”
Section: Discussionsupporting
confidence: 75%
“…4 and 5). On the other hand, various degrees of contrast enhancement of ablated regions represent viable residual tumor (8,30,31) that may progressively increase in size, thus indicating partial ablation (32). Reasons for the existence of residual tumor may be intrinsic heat-resistant properties of a tumor, and residual vascular flow, or reperfusion of an ablation zone (33).…”
Section: Discussionmentioning
confidence: 99%
“…For complete ablation, the ideal is to achieve complete peripheral ground-glass opacity surrounding the tumor, which is not always possible due to emphysema, large tumor size, and structures adjacent to the tumor margin such as a fissure, pleura, or a pulmonary vessel (32). Suh et al (33) observed that at the 3-month follow-up, there was an increase in contrast enhancement compared with that observed at the 1-2-month CT scan.…”
Section: Discussionmentioning
confidence: 99%
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“…12,37 Over a period of a week, the GGO usually changes to more dense airspace opacification. 38 GGO represents a transition from non-viable to viable tissue, and the outer margin of the shadowing probably overestimates the zone of complete ablation by 3-4 mm, emphasizing the need for an adequate treatment margin, analogous to the surgical margin in a resected tumour 39,40 ( Figure 2). It is well known that tumours may extend microscopically into the adjacent lung parenchyma by 6-8 mm, and it is therefore suggested that the ablation zone should be at least 1 cm larger than the lesion.…”
Section: Normal Post-treatment Appearancesmentioning
confidence: 99%