Threat of Dengue to Blood Safety in Dengue-Endemic Countries

Wilder-Smith, Annelies; Chen, Lin H.; Massad, Eduardo; Wilson, Mary

doi:10.3201/eid1501.071097

Cited by 131 publications

(113 citation statements)

References 26 publications

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“…DENV infection has been reported from over 100 countries, in which approximately 2.5 billion people live in endemic regions; the current estimate of the number of annual dengue cases is 100 million for DF and 250,000 for DHF, with a total of 25,000 deaths per year. 5 In fact, these numbers may underestimate the true burden of dengue by almost three times, which was suggested by a recent publication. 6 The pathophysiology of DENV in the body and the host's immune response are not completely understood.…”

Section: Introductionmentioning

confidence: 97%

Micronutrients and Dengue

Ahmed

Finkelstein

Stewart

et al. 2014

The American Society of Tropical Medicine and Hygiene

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Abstract. Dengue virus infection is the most widespread mosquito-borne viral infection in humans and has emerged as a serious global health challenge. In the absence of effective treatment and vaccine, host factors including nutritional status, which may alter disease progression, need investigation. The interplay between nutrition and other infections is well-established, and modulation of nutritional status often presents a simple low-cost method of interrupting transmission, reducing susceptibility, and/or ameliorating disease severity. This review examines the evidence on the role of micronutrients in dengue virus infection. We found critical issues and often inconsistent results across studies; this finding along with the lack of sufficient literature in this field have limited our ability to make any recommendations. However, vitamins D and E have shown promise in small supplementation trials. In summary, the role of micronutrients in dengue virus infection is an exciting research area and needs to be examined in well-designed studies with larger samples.

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Section: Introductionmentioning

confidence: 97%

Micronutrients and Dengue

Ahmed

Finkelstein

Stewart

et al. 2014

The American Society of Tropical Medicine and Hygiene

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“…O dengue é uma doença infecciosa aguda, causada por um vírus da família flavivírus, de grande magnitude epidemiológica e amplitude demográfica, ocasionando grandes epidemias no mundo principalmente nas regiões tropicais, atingindo milhões de pessoas anualmente [1][2][3][4][5][6] . O complexo dengue é formado por quatro sorotipos: Den-1, Den-2, Den-3 e Den-4 4 .…”

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Análise da distribuição espaço-temporal de dengue e da infestação larvária no município de Tupã, Estado de São Paulo

Barbosa

Lourenço

2010

Rev. Soc. Bras. Med. Trop.

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RESUMOMethods: Larval indices were built up block by block and for the entire municipality. We used the cross-lagged correlation method to assess the correlation between dengue cases and larval indices. The kernel estimator was used for spatial analysis. Results: The cross-lagged correlation between dengue cases and larval indices was significant. The kernel estimator maps of positive findings among recipients indicated heterogeneous distribution over the course of the study period. Over two years of transmission, the epidemic occurred in different regions. Conclusions: There was no evidence of a relationship between larval infestation and dengue occurrence. Incorporation of geoprocessing techniques and spatial analysis into the program, if used immediately after completion of activities, might contribute towards the control actions, thereby indicating spatial agglomerations of higher incidence.

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“…Four serotypes of the virus circulate, significantly increasing the severe and lethal forms of the disease 2,3 .…”

Section: Introductionmentioning

confidence: 99%

A ocorrência da dengue e variações meteorológicas no Brasil: revisão sistemática

Viana

Ignotti

2013

Rev. bras. epidemiol.

116

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Introduction: Dengue is configures in recent decades as an important cause of morbidity and mortality in Brazil and around the world reaching the tropical and subtropical areas. Objective: To review the scientific literature on the occurrence of dengue in Brazil and its relationship with meteorological variables. Method: A systematic review of studies published in databases (SciELO, PubMed, MEDLINE, Lilacs) using descriptors related to weather variations and dengue fever in Brazil, published between 1991 to 2010. It was selected 31 articles that had the study area nationwide. Results: Most epidemiological studies use ecological design, the studies make use of entomological trapping, are common also series of studies of the disease and spatial analysis. It is evident relationship between dengue incidence with temperature and rainfall, the association is more significant from the second to fourth months of the year. Comparative studies of drought and rain show seasonal behavior of the disease. There are difficulties in establishing unique pattern of seasonality of disease incidence and weather variables for the country. Conclusion: Dengue is strongly related to meteorological variables. The seasonal variation in temperature and rainfall influences the dynamics of the vector and the incidence of the disease throughout the country, regardless of the climate category. The number of cases of classic dengue and of dengue hemorrhagic fever has been increasing on an annual basis. It is estimated that 550 thousand hospitalizations with 20 thousand deaths occur per year among a total of approximately 2.5 billion exposed people 4,5 , and an average of 80 million new cases are reported every year 2 . KeywordsAs a reemerging endemic or pandemic disease, it occurs practically in all the tropical and subtropical regions of the planet 1 . The countries located in these regions are more susceptible due to diverse conditioning factors, such as: global changes, climate changes, weather variability, land use, water storage and irrigation, human population growth and urbanization 6 . Such factors, among others, significantly contribute to the proliferation and development of the Aedes aegypti mosquito -the virus vector 7-9 . Climate changes contribute to increase the number of people exposed to dengue to more than 2 billion and the projections for 2085 suggest that approximately 5 to 6 billion people (50 to 60% of the world's population) will be at risk regarding the disease transmission 10 .The seasonal dynamics of the dengue vector is commonly associated with climate changes and fluctuations 9,11 , which include: temperature increase and variations in rainfall and relative air humidity, conditions that favor a higher number of available breeding sites and, consequently, the development of the vector. The latter presents two distinct stages: aquatic, with the development phases of egg, larva and pupa, and terrestrial, which corresponds to the adult mosquito. Both stages are subject to environmental and climate changes 12,13 ...

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Threat of Dengue to Blood Safety in Dengue-Endemic Countries

Abstract: Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 15, No.

Cited by 131 publications

References 26 publications

Micronutrients and Dengue

Micronutrients and Dengue

Análise da distribuição espaço-temporal de dengue e da infestação larvária no município de Tupã, Estado de São Paulo

A ocorrência da dengue e variações meteorológicas no Brasil: revisão sistemática

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