Three Antibodies of the MNSs System and Their Association with the Miltenberger Complex of Antigens

Abstract

Abstract. A new antibody in Anek serum reacts with 7% of Thai Mi III donor samples.

MNS Blood Group System

“…Anti -Hop reacted with Mi.IV red cells and with cells of two of the new classes, Mi.VI and Mi.VIII, whereas anti -Nob reacted with Mi.VII and Mi.VIII cells [245,254,297,298] . Anti -Hop reacted with Mi.IV red cells and with cells of two of the new classes, Mi.VI and Mi.VIII, whereas anti -Nob reacted with Mi.VII and Mi.VIII cells [245,254,297,298] .…”

“…(Table 3.10 ). GP.Bun is generally inherited with Ms [297] . In Thais and Chinese, GP.Mur is usually inherited with Ms [219,226] .…”

“…GP.Mur and GP.Bun are always inherited with s. In people of European origin GP.Mur may be inherited with Ns or with Ms , the former being more frequent than the latter [289] . GP.Mur and GP.Bun phenotypes are associated with an elevated expression of ' N ' , the trypsin -resistant N antigen carried on GPB [129,226,289,297,317,318] . GP.Bun is generally inherited with Ms [297] .…”

A survey of the incidence of Miltenberger antibodies among Hong Kong Chinese blood donors

“…Amino acid sequencing shows that variants of glycophorin (GP) A are present in Mi. 1,Mi.11,Mi.VI1,and Mi.VII1 red cells (RBCS). '.~ The abnormal glycoproteins in Mi.111, Mi.IV, and Mi.VI RBCs are hybrid GPs of type (B-A-B),"."…”

Three Antibodies of the MNSs System and Their Association with the Miltenberger Complex of Antigens

“…Chandanayingyong and Pejrachandra [1] were able to produce monospecific anti-Hut from 2 sera with anti-Mur + Hut and anti-Mia by absorption, but they clear ly showed the cross-reactivity of most other reagents. Within the Miltenberger subsystem therefore, there exists the difficulty in de ciding which antisera are truly monospeAs described by Chandanayingyong et al [2], Anek (AY) serum has an antibody which reacted with 7% of Mi III samples in Thailand. 2 other cell types were sub sequently found to react with AY serum, Mi(-) FR, JL(+) and Mi IV (kindly distrib uted by Dr. T. E. Cleghorn).…”