Three-Dimensional Evaluation of Accommodating Intraocular Lens Shift and Alignment In Vivo

Marcos, Susana; Ortíz, Sergio; Pérez-Merino, Pablo; Birkenfeld, Judith; Durán, Sonia; Jiménez-Alfaro, Ignacio

doi:10.1016/j.ophtha.2013.06.025

Cited by 37 publications

(34 citation statements)

References 42 publications

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“…The development of strategies aimed at restoring accommodation such as accommodating intraocular implants, crystalline lens refilling techniques and femtosecond laser softening, have also created the need for in vivo imaging instrumentation that can objectively demonstrate their clinical efficacy [3]. One particular challenge is the difficulty in imaging the ciliary muscle and its interaction with the crystalline lens during accommodation.…”

Section: Introductionmentioning

confidence: 99%

Quantification of the ciliary muscle and crystalline lens interaction during accommodation with synchronous OCT imaging

Ruggeri¹,

Freitas²,

Williams³

et al. 2016

Biomed. Opt. Express

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Two SD-OCT systems and a dual channel accommodation target were combined and precisely synchronized to simultaneously image the anterior segment and the ciliary muscle during dynamic accommodation. The imaging system simultaneously generates two synchronized OCT image sequences of the anterior segment and ciliary muscle with an imaging speed of 13 frames per second. The system was used to acquire OCT image sequences of a non-presbyopic and a pre-presbyopic subject accommodating in response to step changes in vergence. The image sequences were processed to extract dynamic morphological data from the crystalline lens and the ciliary muscle. The synchronization between the OCT systems allowed the precise correlation of anatomical changes occurring in the crystalline lens and ciliary muscle at identical time points during accommodation. To describe the dynamic interaction between the crystalline lens and ciliary muscle, we introduce accommodation state diagrams that display the relation between anatomical changes occurring in the accommodating crystalline lens and ciliary muscle.

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Section: Introductionmentioning

confidence: 99%

Quantification of the ciliary muscle and crystalline lens interaction during accommodation with synchronous OCT imaging

Ruggeri¹,

Freitas²,

Williams³

et al. 2016

Biomed. Opt. Express

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“…Three-Dimensional Evaluation of Accommodating Intraocular Lens Shift and Alignment in vivo Quantitative 3-D anterior segment OCT allows full evaluation of the geometry of eyes Implanted with A-IOLs preoperatively and postoperatively [42].…”

Section: Bmentioning

confidence: 99%

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2017

RMES

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“…The biometrical parameters necessary to build the computer eye model were obtained from OCT (anterior and posterior corneal radius, corneal thickness, ACD) 4 and from noncontact profilometry (anterior and posterior IOL radii of curvature and thickness). Table 1 shows the corresponding parameters for all five eyes.…”

Section: Iol Tilt and Decentration In Patientsmentioning

confidence: 99%

“…3 Finally, tilts and decentrations occurring with the only U.S. Food and Drug Administration (FDA)-approved A-IOL may also play a role in its function. 4 Measurement of tilt and decentration of IOLs in pseudophakic eyes is therefore important as an endpoint for treatment, particularly with premium IOLs. On the other hand, in combination with biometrical and anatomical ocular data, knowledge of IOL and eye alignment is important in the development of customized computer eye models, which give insights into the relative contribution of different factors to optical performance with IOLs (Refs.…”

Section: Introductionmentioning

confidence: 99%

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Intraocular lens alignment from an en face optical coherence tomography image Purkinje-like method

et al. 2014

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Abstract. Measurement of intraocular lens (IOL) alignment implanted in patients in cataract surgery is important to understand their optical performance. We present a method to estimate tilt and decentration of IOLs based on optical coherence tomography (OCT) images. En face OCT images show Purkinje-like images that correspond to the specular reflections from the corneal and IOL surfaces. Unlike in standard Purkinjeimaging, the tomographic nature of OCT allows unequivocal association of the reflection with the corresponding surface. The locations of the Purkinje-like images are linear combinations of IOL tilt, IOL decentration, and eye rotation. The weighting coefficients depend on the individual anterior segment geometry, obtained from the same OCT datasets. The methodology was demonstrated on an artificial model eye with set amounts of lens tilt and decentration and five pseudophakic eyes. Measured tilt and decentration in the artificial eye differed by 3.7% and 0.9%, respectively, from nominal values. In patients, average IOL tilt and decentration from Purkinje were 3.30 AE 4.68 deg and 0.16 AE 0.16 mm, respectively, and differed on average by 0.5 deg and 0.09 mm, respectively, from direct measurements on distortion-corrected OCT images. Purkinje-based methodology from anterior segment en face OCT imaging provided, therefore, reliable measurements of IOL tilt and decentration.

show abstract

Three-Dimensional Evaluation of Accommodating Intraocular Lens Shift and Alignment In Vivo

Cited by 37 publications

References 42 publications

Quantification of the ciliary muscle and crystalline lens interaction during accommodation with synchronous OCT imaging

Quantification of the ciliary muscle and crystalline lens interaction during accommodation with synchronous OCT imaging

Untitled

Intraocular lens alignment from an en face optical coherence tomography image Purkinje-like method

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