2002
DOI: 10.1109/10.972834
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Three-dimensional finite-element analyses for radio-frequency hepatic tumor ablation

Abstract: Abstract-Radio-frequency (RF) hepatic ablation, offers an alternative method for the treatment of hepatic malignancies. We employed finite-element method (FEM) analysis to determine tissue temperature distribution during RF hepatic ablation. We constructed three-dimensional (3-D) thermal-electrical FEM models consisting of a four-tine RF probe, hepatic tissue, and a large blood vessel (10-mm diameter) located at different locations. We simulated our FEM analyses under temperature-controlled (90 C) 8-min ablati… Show more

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Cited by 297 publications
(195 citation statements)
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“…Since there is no tissue perfusion in swine liver in in vitro experiments, we exclude parameters for blood perfusion from FE models. Location of the targeted liver tumor in relation to large blood vessels can also change the dimensions, as well as characteristics of resulted coagulation zones [34]. A nonuniform heating MW ablation system might be beneficial to properly ablated both regions close to large blood vessels (more heat) and those that are further away(less heat).…”
Section: Discussionmentioning
confidence: 99%
“…Since there is no tissue perfusion in swine liver in in vitro experiments, we exclude parameters for blood perfusion from FE models. Location of the targeted liver tumor in relation to large blood vessels can also change the dimensions, as well as characteristics of resulted coagulation zones [34]. A nonuniform heating MW ablation system might be beneficial to properly ablated both regions close to large blood vessels (more heat) and those that are further away(less heat).…”
Section: Discussionmentioning
confidence: 99%
“…They range from simple geometric models that use ellipsoids to describe the necrosis [11] over time dependent PDE models with constant coefficients [13,16] to complex models that take cell water evaporation and temperature dependent material parameters into account [14,15,17]. Some authors exploit rotational symmetry around the applicator axis [12], which is of course impossible if the aim is to consider patient individual vascular systems.…”
Section: 1)mentioning
confidence: 99%
“…The way in which vascular cooling is taken into account varies considerably: Simple models use heuristics to quantify the cooling effects [11] or do not consider patient individual vascular systems at all [12]. More advanced approaches model individual vessels by a fixed heat sink [13,14], and some authors even take blood flow together with heat exchange between vessel and tissue into account [15][16][17]. For a comprehensive review, see the overview article by Berjano [18].…”
Section: Introductionmentioning
confidence: 99%
“…The details of the FEM and its implementation for bioelectromagnetic problems are available. [74][75][76][77][78][79][80][81][82][83][84][85][86] …”
Section: Iib Modeling Power Depositionmentioning
confidence: 99%