The traditional structural performance may be seriously degraded due to applied indeterministic cases. A novel framework for robust topology optimization of truss-like continuum considering uncertain loads is presented. The robust optimization formula is constructed as minimizing the weighted sum of expectancy and standard variance of structural compliance with volume constraints. In this framework, both the magnitude and direction of applied loads are uncertain and independent. Truss-like continuum provides the topology optimal structure theoretically. Based on the classic truss-like optimization method, the statistical moments of compliance are accurately evaluated utilizing a bivariate cloud model tool. An effective strategy based on linear decoupling is reported to largely reduce the total number of finite element analysis. The optimization is achieved with gradient-based mathematic programming. Several numerical examples demonstrate a better structural robust performance obtained by the proposed algorithm than the traditional one.