“…There are different kinds of PSIO treatment approaches with different mechanics, all seeking and achieving different objectives (Friede et al, 1998;Kuijpers-Jagtman et al, 2000;Prahl-Andersen, 2000;Ross et al, 2000;Watson et al, 2004;Berkowitz, 2006). Among these, presurgical nasoalveolar molding (PNAM) appliances have generated considerable interest in recent years and have been in use as a new approach to traditional presurgical infant orthopedics (TPSIO) Maull et al, 1999;Grayson et al, 2001;Suri and Tompson, 2004;Singh et al, 2005). Some of the major advantages of TPSIO are claimed to be the improvement of arch form, the facilitation of surgical closure, and thus improvement of aesthetic outcome, the facilitation of feeding, and improvement of speech (Ross and MacNamera, 1994;Kuijpers-Jagtman et al, 2000;Mishima et al, 2000;Prahl et al, 2001;Konst et al, 2004;Berkowitz, 2006).…”