Three-dimensional quantitative measurements of atrophy and fat infiltration in sub-regions of the supraspinatus muscle show heterogeneous distributions: a cadaveric study

Trevino, Jose H.; Yuri, Takuma; Hatta, Taku; Kiyoshige, Yoshiro; Jacobs, Philip M.; Giambini, Hugo

doi:10.1007/s00402-021-03765-8

Cited by 10 publications

(9 citation statements)

References 36 publications

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“…Our data demonstrate that 3D muscle volumetry should be preferred in patients with full-thickness SSP tendon tears when the muscle volume needs to be quantified preoperatively in order to estimate the postoperative success rate after tendon repair procedures. This is in accordance with previous studies [ 17 ] and is important since various previous experimental and clinical studies have shown that significant SSP muscle atrophy is an important adverse prognostic factor affecting patients’ outcomes in addition to other conditions, e.g., fatty infiltration or severe tear size [ 8 , 18 , 19 , 20 , 21 , 22 , 23 , 24 ].…”

Section: Discussionsupporting

confidence: 92%

Three-Dimensional Software- and MR-Imaging-Based Muscle Volumetry Reveals Overestimation of Supraspinatus Muscle Atrophy Using Occupation Ratios in Full-Thickness Tendon Tears

et al. 2022

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Supraspinatus muscle atrophy is widely determined from oblique-sagittal MRI by calculating the occupation ratio. This ex vivo and clinical study aimed to validate the accuracy of 3D software- and MR-imaging-based muscle volumetry, as well as to assess the influence of the tear pattern on the occupation ratio. Ten porcine muscle specimens were volumetrized using the physical water displacement volumetry as a standard of reference. A total of 149 individuals with intact supraspinatus tendons, partial tears, and full-thickness tears had 3T MRI. Two radiologists independently determined occupation ratio values. An excellent correlation with a Pearson’s r of 0.95 for the variables physical volumetry using the water displacement method and MR-imaging-based muscle volumetry using the software was found and formed the standard of reference for the patient study. The inter-reader reliability was 0.92 for occupation ratios. The correlation between occupation ratios and software-based muscle volumes was good in patients with intact tendons (0.84) and partial tears (0.93) but considerably lower in patients with full-thickness tears (0.68). Three-dimensional-software- and MR-imaging-based muscle volumetry is reliable and accurate. Compared to 3D muscle volumetry, the occupation ratio method overestimates supraspinatus muscle atrophy in full-thickness tears, which is most likely due to the medial retraction of the myotendinous unit.

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Section: Discussionsupporting

confidence: 92%

Three-Dimensional Software- and MR-Imaging-Based Muscle Volumetry Reveals Overestimation of Supraspinatus Muscle Atrophy Using Occupation Ratios in Full-Thickness Tendon Tears

et al. 2022

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“…According to previous protocols, 21,36 the Global-FI throughout the SSP muscle was identified by the global 3-dimensional (3D)–volumetric fatty fraction within the whole muscle volume. The semiautomatic volumetric SSP segmentation was performed via ITK-SNAP, generating a 3D model for volume assessments (Figure 1B).…”

Section: Methodsmentioning

confidence: 99%

“…Therefore, the global volumetric fatty fraction was acquired as the ratio of fat volume to the muscle volume according to equation 4, representing the Global-FI within the whole SSP. 21,36 Global-FI 5 Fat volume Muscle volume…”

Section: Global-fi Measurements In the Whole Sspmentioning

confidence: 99%

The Modified Assessment Tool Based on Scapular Y-View for Global Fatty Infiltration in the Supraspinatus Muscle: Correlation, Predictive Performance, and Reliability Analyses

Liu

Han

et al. 2023

Am J Sports Med

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Background: The accurate evaluation of rotator cuff (RC) fatty degeneration after tears is critical for appropriate surgical decision making and prognosis. However, there is currently no reliable and practical tool to reflect the global fatty infiltration (Global-FI) throughout the 3-dimensional (3D) volumetric RC muscles. Purpose: (1) To determine the correlations between 2 modified assessment tools and the Global-FI and their predictive performances and reliabilities for Global-FI prediction, and (2) to compare these predictive parameters with those of the conventional tool using a single scapular Y-view slice. Study Design: Cohort study (diagnosis); Level of evidence, 3. Methods: A total of 49 patients with full-thickness RC tears scheduled to undergo arthroscopic repairs were included, and their surgical shoulders underwent 6-point Dixon magnetic resonance imaging preoperatively. The Global-FI was measured by calculating the 3D-volumetric fat fraction (FF) of the whole supraspinatus muscle through all acquired oblique sagittal slices. As a commonly used radiological landmark, the scapular Y-view was used to evaluate single-plane fatty infiltration (Y-FI) by calculating the FF in 1 slice, defined as the conventional assessment tool. Two modified assessment tools expand the analytic imaging by integrating the FFs from the scapular Y-view slice and its neighboring slices, which were calculated by averaging the FFs of these 3 slices (meanY3-FI) and accumulating local 3D-volumetric FFs from 3 slices (volY3-FI), respectively. The correlations between 3 assessment tools and the Global-FI were analyzed, and the predictive performance for Global-FI prediction using these tools was determined by goodness of fit and agreement. Moreover, the inter- and intraobserver reliabilities of these assessment tools were evaluated. Similar analyses were performed in the small-medium, large, or massive tear subgroups. Results: The Y-FI was significantly higher than the Global-FI in all cases and tear size subgroups, while the 2 modified assessment tools (meanY3-FI and volY3-FI) did not significantly differ from the Global-FI. All assessment tools were significantly correlated with the Global-FI, but the meanY3-FI and volY3-FI showed stronger correlations than the Y-FI, which was also determined in different tear sizes. Moreover, the regression models of the meanY3-FI and volY3-FI showed superior goodness of fit to Y-FI in Global-FI prediction in all cases and subgroups, with larger coefficients of determination ( R2) and smaller root mean square errors. The predicted Global-FI using the regression model of volY3-FI had the best agreement with the measured Global-FI, followed by the meanY3-FI, both showing smaller biases and standard deviation of the percentage difference between predicted- and measured Global-FI than the conventional Y-FI. In addition, the 2 modified assessment tools achieved better interobserver and intraobserver reliabilities than the conventional tool in all cases and subgroups. Conclusion: Two modified assessment tools (meanY3-FI and volY3-FI) were comparable with the Global-FI of the whole supraspinatus muscle, showing stronger correlations with the Global-FI and better predictive performances and reliabilities than the conventional tool (Y-FI). Moreover, the volY3-FI was slightly superior to meanY3-FI in the predictive performance and reliability.

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“…Several studies have demonstrated that, in the setting of a rotator cuff tear, the superficial subregion of the SSP primarily atrophies, while the deep subregions mainly show fat infiltration (25,26). Kim et al showed that the fiber type distribution of the anterior superficial subregion was mainly comprised of Type II fibers, while that of the anterior middle was Type I (27).…”

Section: Discussionmentioning

confidence: 99%

Coordination of the Sub-Regions of the Supraspinatus and Deltoid Muscles During Shoulder Scaption: a Shear Wave Elastography Study

Hoshikawa¹,

Yuri²,

Mura³

et al. 2021

Muscle Ligaments and Tendons J

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Background. Understanding the functional role of the supraspinatus (SSP) and deltoid muscles during shoulder motion is a basis for understanding rotator cuff pathology and for the development of appropriate rehabilitation protocols. The purpose of this study was to elucidate the coordination, focusing on activation timing, of the sub-regions of the SSP muscle and of the middle region of deltoid muscle during scapular plane abduction (scaption) using shear wave elastography (SWE). Methods. Twelve healthy male volunteers without any restrictions in their shoulder joints, altered posture or scapulothoracic dyskinesis were recruited to this study. Participants were instructed to sit on a chair with their back against the back-rest. Measurements of the non-dominant arm were obtained at rest and during isometric contraction at a neutral position and every 15° interval from 30° to 150° during scaption. Muscle activity was defined as the difference in SWE-measured stiffness between resting outcomes and those measured during muscle contraction (∆E = stiffness during contraction -stiffness at rest). Results. The anterior-middle sub-region of the SSP muscle and the middle region of the deltoid muscle presented a mountain-shape type curve with peaks at 60° (146.2 ± 26.6 kPa) and at 90° (142.0 ± 25.9 kPa), respectively. The anterior-superficial sub-region of SSP muscle peaked at 30° (102.1 ± 27.4 kPa), linearly decreasing thereafter. Conclusions. The anterior-superficial sub-region of the SSP muscle showed activity during initial range of motion, while the anterior-middle sub-region showed activity at early mid-range. On the contrary, the middle region of the deltoid muscle showed increased SWE-measured activity at late mid-range. A more refined approach focusing on the muscles sub-regions may lead to improved rehabilitation protocols.

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Three-dimensional quantitative measurements of atrophy and fat infiltration in sub-regions of the supraspinatus muscle show heterogeneous distributions: a cadaveric study

Cited by 10 publications

References 36 publications

Three-Dimensional Software- and MR-Imaging-Based Muscle Volumetry Reveals Overestimation of Supraspinatus Muscle Atrophy Using Occupation Ratios in Full-Thickness Tendon Tears

Three-Dimensional Software- and MR-Imaging-Based Muscle Volumetry Reveals Overestimation of Supraspinatus Muscle Atrophy Using Occupation Ratios in Full-Thickness Tendon Tears

The Modified Assessment Tool Based on Scapular Y-View for Global Fatty Infiltration in the Supraspinatus Muscle: Correlation, Predictive Performance, and Reliability Analyses

Coordination of the Sub-Regions of the Supraspinatus and Deltoid Muscles During Shoulder Scaption: a Shear Wave Elastography Study

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