Three Examples of a New Red Cell Antibody, Anti‐Co^a

A Further Example of Anti-Co^a and two Informative Families with Co(a-) Members

“…These results confirm the findings of Heistö et al [1] that Coa is not part of the MN Ss, Rh or Kidd systems or a sex linked character and extend them to show that it is probably not controlled by the Lewis or secretor loci.…”

“…The Lewis genotype of II-l could be LeLe or Lele; that of II-2 must be lele. As Heistö et al [1] have pointed out, if Co(a-) sibs differ in genotype for a particular blood group system, Coa cannot be controlled by the locus for that system provided that both parents are Co(a+). Thus the Lewis and Rh loci are not responsible for the presence or absence of Coa.…”

“…Toronto and Halifax Depots, Canadian Red Cross Blood Transfusion Service Anti-Coa (Calton), antigen Coa of very high frequency, van der Hart, Madsen, Moss, Noades, Pickles, Race, Sanger, and Swanson [1] in 1967. Three examples were described.…”

Further Examples of the Wulfsberg Antigen

“…In 1966 the blood group antigen Wu (Wulfsberg) was discovered by Heisto [2] whilst carrying out routine screening for antibodies when by chance, Wu-positive cells were being used. In 5 studies of Norwegian populations the antigen incidence was 1 in 9,163 [2,5,6], and the antibody incidence was 4 in 9,634 [2,5].…”

Anti‐Coa implicated in severe haemolytic disease of the foetus and newborn

“…Anti‐Colton (Co a ) antibody was described by Heistö et al (1967). The incidence of Co(a+) antigen in Caucasian people is about 99·8% and that of Co(b+) is about 8% (Daniels, 2002).…”