Three new eudesmanes from Artemisia japonica

Abstract

Three new eudesmanes, named artemisidiols A-C, together with eight known compounds, were isolated from the leaves of Artemisia japonica Thunb. (Asteraceae). Their structures were determined on the basis of spectroscopic data. Although oxygenated eudesmanes frequently occur in Asteraceae plants, the 1α,6α,8α-oxygenated pattern of artemisidiols A-C has not been previously reported.

Extraction optimisation using water/glycerol for the efficient recovery of polyphenolic antioxidants from two Artemisia species

“…Approximately one-half of all licensed drugs that were registered worldwide in the 25 y period prior to 2007 were natural products or their synthetic derivatives [1]. The Asteraceae family includes over 20,000 species and more than 500 species from the genus Artemisia grow mainly in Asia, Europe and North America, some of which are economically important [2]. Artemisia species contain a large spectrum of secondary metabolites, including terpenoids, flavonoids, coumarins, caffeoylquinic acids and polyacetylenes [3], and several of them are frequently used for the treatment of diseases such as hepatitis, cancer, malaria, inflammation, and infections by fungi, bacteria and viruses [4].…”

Evaluación del efecto de las artemisininas provenientes del extracto etanólico de Artemisia cina sobre L3 de Haemonchus contortus en una técnica de explantes abomasales

“…Giang et al (22) han notificado más de 500 especies del género Artemisia con gran cantidad de compuestos, entre ellos terpenoides, flavonoides, cumarinas, ácidos cafeoilquinas, poliacetilenos con variaciones oxidativas o estereoquímicas, que son probablemente compuestos obtenidos de las fracciones en estudio, pero que aún falta por caracterizar.…”

“…En un estudio similar, realizado por Giang et al (22), su muestra que el mejor mecanismo para separar los compuestos de A. japonica era con N-hexano, diclorometano y acetato de etilo. Este estudio buscaba separar terpenos e isómeros derivados de las artemisininas, al mejorar la obtención de compuestos no polares.…”

Chemical composition of hexane and chloroform extracts from Artemisia scopaeformis

“…However, despite significant progress is being made in the disclosure of the chemical composition and bioactivities of herbal medicines, their exact biological functions and regulation mechanisms largely remain to be clarified. Medicinal plants with the ancient history of human use have been considered one of the important and reliable sources to discover promising therapeutic agents in a number of cases, including cancer chemopreventive drugs [3][4][5].…”