Three patients with arteritis.

Eke, F U; Balfe, J. Williamson; Hardy, Brian

doi:10.1136/adc.59.9.877

Cited by 16 publications

(12 citation statements)

References 44 publications

(3 reference statements)

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“…As in other reports, pharmacological management in five of our six patients was quite disappointing [6,7,9,16,34,35]. This refractoriness to medical management can be largely explained on the basis of the one-kidney, one-clip Goldblatt model of hypertension which best resembles the clinical aspects of bilateral RAS [36,37].…”

Section: Management Of Bilateral Rasmentioning

confidence: 68%

“…In addition to our six cases, Table 2 summarizes the data from 36 children reported over the last decade in which it is possible to determine treatment and outcome of bilateral RAS [4][5][6][7][8][9]. Not included in Table 2 are data from three large series which included another 64 children with bilateral RAS in whom such information is not available [10][11][12].…”

Section: Discussionmentioning

confidence: 95%

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Evaluation and management of bilateral renal artery stenosis in children: A case series and review

et al. 1995

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This report describes the clinical course, diagnostic evaluation and management of six children with bilateral renal artery stenosis (RAS) and concurrent narrowing of the abdominal aorta. Except for one child with active arteritis, the others were asymptomatic. There were no clinical or laboratory features suggesting the etiology of hypertension in four of six patients, and diagnostic procedures, including Doppler duplex ultrasound and captopril scintigraphy, were unreliable in screening for such hypertension. Abdominal aortography and selective renal angiography confirmed the diagnosis of bilateral RAS and associated anatomical alterations of the aorta and its branches. The hypertension was severe and minimally responsive to antihypertensive agents. It was cured or improved after percutaneous transluminal angioplasty (PTA) of three vessels in two children with mid-vessel stenoses, while hypertension persisted after PTA of two mid-vessel stenoses in a third child and one vessel with ostium stenosis in a fourth child. Autotransplantation of seven kidneys in four children resulted in cure of significant improvement of the hypertension. Renal function was preserved in all children during a mean follow-up time of 41 months. Based on illustrative data from these six children, as well as information from a review of the literature, this report discusses the key diagnostic issues and stresses the potential advantages of renal autotransplantation in selected children with this disorder.

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Section: Management Of Bilateral Rasmentioning

confidence: 68%

Section: Discussionmentioning

confidence: 95%

Evaluation and management of bilateral renal artery stenosis in children: A case series and review

et al. 1995

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“…The age of onset may vary from infancy [11, 12] to middle age. In a series of 60 patients with TA at the National Institute of Allergy and Infectious Diseases in North America, 30% were younger than 20 years at diagnosis [10].…”

Section: Epidemiologymentioning

confidence: 99%

Large vessel vasculitis

Gulati

Bagga

2009

Pediatr Nephrol

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Takayasu arteritis is a chronic granulomatous disease of the aorta and its major branches that usually affects women during the second and third decades of life, but it has been reported in young children. This review details the clinical, pathological and radiological features, differential diagnoses and management of the condition, focusing chiefly on the disease in children. The recent definition of Takayasu arteritis is discussed. The condition should be considered in patients with unexplained arterial hypertension or unexplained inflammatory syndromes without signs of localization. Since the disease may be life-threatening and progressive, early recognition is necessary to initiate appropriate therapy. Patients with persistent ischaemic symptoms including hypertension might benefit from revascularization procedures.

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“…usually TA affects young women, most often been reported in young east Asian women (median age at onset, 25 years), in their second and third decades of life, and the age at onset is usually between 15 and 30 years 1,3 . However, the age at onset may vary from infancy 1,[4][5][6][7][8] to middle age. Although TA can affect both sexes and all races, women with TA outnumber men by 8-9:1 1 .…”

Section: Introductionmentioning

confidence: 99%

Aggressive Progression of Takayasu’s Arteritis in Infancy: A Case Report

Pavić

2019

ACC

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-Takayasu's arteritis (TA) affects the aorta and its branches. immunosuppressants are the usual course of therapy, while surgery has been used in acute cases. There is only scant information on TA in infancy, and the nonspecific symptoms in the initial stage of the disease make the diagnosis difficult and delayed, thus increasing the mortality rate. We describe a case of aggressive progression of TA in an infant. This child was the youngest to be affected with the disease as reported in the literature. A 3.5-month-old boy presented with cyanosis of both legs, tachycardia and antithrombin iii deficiency. Computed tomography angiography (CTA) revealed thrombosis of distal aorta and both iliac arteries. Thrombectomy was performed at the level of both common femoral arteries. in addition, thigh amputation of the left leg had to be performed. TA was diagnosed postmortem with thrombosis of the distal aorta, its branches and upper mesenteric artery which was not occluded on previous CTA, glomerulonephritis and pulmonary parenchymal granulomatous infiltrations.

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Three patients with arteritis.

Cited by 16 publications

References 44 publications

Evaluation and management of bilateral renal artery stenosis in children: A case series and review

Evaluation and management of bilateral renal artery stenosis in children: A case series and review

Large vessel vasculitis

Aggressive Progression of Takayasu’s Arteritis in Infancy: A Case Report

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