Three years with a national apheresis registry

Abstract

The large number of unsolved problems in plasma exchange therapy makes an apheresis registry appear useful. The results of such an open prospective observational study from 1987 to 1989 in East Germany are presented in this paper. With 1,945 procedures in a total of 419 patients (on average 4.1 treatments per patient) about 80% of all treatments in the country were registered. Exchange volume averaged 2.7 (+/- 0.78) l or 43 (+/- 13.9) ml/kg body weight. Substitutes were albumin (51% of the cases), FFP (22%), and both (22%). Nephrological (25%) and neurological (23%) diagnoses prevailed among the treated diseases. Haematologic diseases (12%) were underrepresented and hepatic coma (20%) was overrepresented. Minor side effects occurred in 22% of all treatments and severe complications in 38 treatments (2%). Four fatalities probably resulted from plasmapheresis therapy. The registry permits an assessment of the treatment results and of several trends during the period of observation.

Therapeutic Apheresis in Taiwan

“…A national apheresis registry on the contents of TA has been done in Canada (5,6), France (7,8), Germany (9), the United States (10), and Japan (11). The safety, clinical indication, and clinical efficacy of TA were confirmed in these surveys although the apheresis modalities and applicable disorders may be different among countries (1).…”

“…A nationwide apheresis registry is beneficial for the understanding of the current status of TA in clinical practice and for the expansion of appropriate and applicable indications for TA. In the countries that are advanced in the concept and technology of TA, national apheresis registries on the contents of TA have been regularly performed (5–11). In Taiwan, the use of TA, particularly for the management of patients with neurological and hematological disorders, has steadily increased since the early 1990s.…”

The Italian registry of pediatric therapeutic apheresis: A report on activity during 2005

“…Several national and international apheresis societies have promoted the establishment of special registries to collect data to be analyzed [5][6][7][8][9][10][11][12][13][14][15]. Periodical surveys of apheresis activity have thus been carried out by the Italian Society of Hemapheresis and Cellular Manipulation (SIdEM) beginning in 1996 [16,17].…”

Toxicity of the staphylococcal protein A immunoadsorption column

“…Schmitt et a1 reported this year on a three year experience with a National Registry in Germany. There were four fatalities in 1,945 procedures which they felt resulted from the plasmapheresis therapy [6]. So, even without 0 1992 Wiley-Liss, Inc.…”