Background: Pulmonary embolism (PE) is a relatively common cardiovascular emergency. Acute PE is the most serious clinical presentation of venous thromboembolism. PE is the consequence of deep vein thrombosis (DVT). The aim was to assess clinical presentation, risk stratification and management of different Egyptian's patients with suspected diagnosis of acute pulmonary embolism. Results: Our study is reported that 33.5% of the DVT patients had silent PE, Patient's risk Stratification showed that 5(5%) had high risk Stratification, 11(11%) had intermediate risk Stratification and 82(82%) had low risk Stratification, Patient's treatment showed that 94(94%) had to take enoxaparine, 3(3%) had to take UF Heprin and warfarin and 3(3%) had to take enoxaparine, warfarine and streptokinase, and Patient's outcome showed that in hospital 4(4%) were death and 7(7%) had bleeding (4(57.1%) hematuria, 2(28.6%) ecchymosis and 1(14.3%) intrauterine). Conclusion: Females are more susceptible to pulmonary embolism than males. Most of patients are above age of 50 y. Most of patients have intermediate Wells score. Most of patients have tricuspid regurge and pulmonary hypertension with normal left and right ventricular function. Most of patients have low risk stratification. Anticoagulants are the main treatment like heparin and warfarin.