Thrombus straddling a patent foramen ovale and pulmonary embolism: A case report

Huang, Yuan; Chen, Yu; Cao, Yu; Qiu, Yi-Gang; Zheng, Jie; Li, Tianchang

doi:10.12998/wjcc.v8.i20.4902

Cited by 2 publications

(2 citation statements)

References 15 publications

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“…The main mechanism of syncope in PFO patients may be paradoxical embolism. Therefore, we speculate that the possible mechanism of syncope caused by PFO is as follows: (1) The emboli formed by the repeated opening of the foramen ovale or by lower extremity veins fall off and enter the left atrium, from which they are pushed into the systemic circulation with the pumping of blood, resulting in arterial embolisms that may cause stroke, myocardial infarction, and syncope ( 33 , 34 ). (2) Venous blood is largely shunted from the right atrium to the left heart system and mixed arteriovenous blood supplies the brain, which can cause transient cerebral ischemia and hypoxia, resulting in syncope ( 35 – 37 ).…”

Section: Discussionmentioning

confidence: 99%

Correlation between percutaneous patent foramen ovale closure and recurrence of unexplained syncope

Wang

Liu²,

Zheng³

et al. 2023

Front. Neurol.

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BackgroundThe relationship between patent foramen ovale (PFO) and unexplained syncope remains to be illustrated. Therefore, this study aimed to explore the outcomes and prognostic factors for syncope recurrence after PFO closure.MethodsPatients with both large right-to-left shunting (RLS) PFO and unexplained syncope who visited the cardiovascular department of Xiangya Hospital Central South University from 1 January 2017 to 31 December 2021 were consecutively enrolled in our study. The recurrence rate of syncope was compared between the non-closure group (n = 20) and the closure group (n = 91).ResultsA total of 111 patients were finally included. After 31.11 ± 14.30 months of follow-up, only 11% of patients in the closure group had recurrent syncope, which was much lower than that of the non-closure group (11.0 vs. 35%, P = 0.018). We further investigated the possible prognostic factors for syncope recurrence in the closure group and found syncope occurring more than five times preoperatively, hypertension, and residual RLS at 12-month follow-up were significantly correlated with a higher number of recurrences.ConclusionsPFO closure reduced the recurrence rate of unexplained syncope. The efficacy of prevention was prognosticated by factors including the presence or absence of syncope induction, the frequency of syncope episodes, and the presence or absence of hypertension. Syncope recurrence was also related to residual shunts post closure.

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Section: Discussionmentioning

confidence: 99%

Correlation between percutaneous patent foramen ovale closure and recurrence of unexplained syncope

Wang

Liu²,

Zheng³

et al. 2023

Front. Neurol.

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“…Thrombus straddling PFO is rarely documented due to its transient nature, complicating with pulmonary embolism is a critical condition and associated with high mortality. 1,2 Management remains controversial, thrombolysis may cause hemorrhage, and disruption of a fixed thrombus leading to new embolism events. 3 So, monitoring of thrombolysis in time is essential to subsequent treatment.…”

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confidence: 99%

Monitoring large thrombus straddling patent foramen ovale using cardiac point‐of‐care ultrasound

Sun

Fang

et al. 2021

J of Clinical Ultrasound

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Thrombus straddling a patent foramen ovale and pulmonary embolism: A case report

Cited by 2 publications

References 15 publications

Correlation between percutaneous patent foramen ovale closure and recurrence of unexplained syncope

Correlation between percutaneous patent foramen ovale closure and recurrence of unexplained syncope

Monitoring large thrombus straddling patent foramen ovale using cardiac point‐of‐care ultrasound

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