Thymic Hassall’s corpuscles in Nandanam chicken - light and electronmicroscopic perspective (Gallus domesticus)

Abstract

The present study was aimed to study the light and electron microscopic studies of thymic Hassall’s corpuscles was done in various age groups of Nandanam Chicken ranging from day-old to forty weeks. Hassall’s corpuscles are special, unique structures present in thymic medulla and also in the cortex of all the age groups of Nandanam chicken (from hatch to forty weeks) in the present study. Size of the Hassall’s corpuscles in the medulla is larger than the ones present in the cortical region of thymus. The Hassall’s corpuscles are made up of structureless eosinophilic mass surrounded by concentrically arranged reticuloepithelial cells. Under electron microscope, the Hassall’s corpuscles were composed of reticuloepithelial cells interconnected by many desmosomes. The epithelial cells had abundance of cytoplasmic fibrils and desmosomes with few mitochondria and ribosomes. The nucleus was oval or round which was slightly indented. The centre of the Hassall’s corpuscles was appeared either solid or cystic. The cystic corpuscles had cell debris within the cyst lumen.

Histomorphological Study of Thymus in Japanese Quail (Coturnix coturnix japonica)

“…It was observed that, group of cyst coalesced to form the larger cysts (Fig 6 and 7). These observations are in agreement with the findings reported by Kannan et al (2015) in fowl. Hashimoto and Sugimura (1976) in Pekin duck reported the similar morphology of cyst.…”

“…These observations of the present findings are in line with reports made by Kannan et al (2015) in fowl, Gulmez and Aslan (1999) in Geese, Tamilselvan et al (2017) in Guinea fowl, Hashimoto and Sugimura (1976) in Pekin duck and Senapati et al (2015) in quail, chicken and duck. Th ese work ers repo rted the sim ilar morphology of Hassall's corpuscles.…”

Post-Aire Medullary Thymic Epithelial Cells and Hassall’s Corpuscles as Inducers of Tonic Pro-Inflammatory Microenvironment

“…In addition to the conventional mTECs described above, the thymic medulla contains unique structures called Hassall’s corpuscles (HCs). These structures, firstly characterized in 1846 by Arthur Hill Hassall ( 38 ) in human thymi have, after their initial description, been found in several other mammals ( 39 ) but as well as in bird and fish species ( 40 , 41 ). In humans, the HCs appear as a concentric merged cluster of unnucleated cells with a typical diameter of 20-100 μm and are present in large quantities already by the 28 th week of prenatal development ( 42 ).…”

Anatomo-topographic and histo-cytological study of dromedary’s spleen in Algeria

“…The spleen is the largest secondary lymphoid organ in mammals and also the primary site for proliferation and differentiation of immune cells and has been described as a center of blood filtration [4]. The splenic parenchyma has a crucial role in immune responses such as exposure to antigens transmitted by blood according to studies by [10].…”