Thymoquinone-Loaded Essential Oil–Based Emulgel as an Armament for Anti-psoriatic Activity

Preparation of Nanoemulgels Containing Lemon Essential Oil and Pectin: Physical Stability and Rheological Properties

“…Emulgels exhibited a shear thinning behavior which is typical of non-Newtonian fluids. This flow behavior was observed by other authors who also studied emulgels [2,27]. These authors explained the decrease in viscosity with the increase in shear rate by a decrease in contact, and therefore a decrease in interactions, between the polymer chains.…”

“…Several papers on emulgels containing essential oils can be found in the literature. By way of an example, it is worth mentioning the work published by Kharat et al (2022) [27] who studied emulgels formulated with tea tree oil and thymoquinone to be used to reduce psoriasis disease, or the articles reported by Srivastava et al (2018) [28] and da Silva et al (2021) [29] for the treatment of vaginal candidiasis by the formulation and preparation of an emulgel containing mentha essential oil and clove oil, respectively, or Abdallah et al (2023) [30] who after optimizing the formulation of erythromicynin-loaded transethosomes obtained erytromicynin-loaded transethosomes in cinnamon-oil-based emulgels to treat topical bacterial infections, or Azam et al (2023) [31] who evaluated anisebased emulgels to also treat skin infections caused by bacteria. Emulsifiers are adsorbed at the oil/water interface, facilitating not only the formation of the emulsion but also its physical stability, thus allowing the shelf life of the emulgel to be prolonged.…”

Multifunctional Wound Curation Dressing Material FemuFrost─An Antioxidant-Loaded Nanoemulsion Frosted Patch of Poly(vinyl alcohol) and Hyaluronic Acid

“…The FA loaded LMGO based nanoemulsion was prepared by the previously reported method . The FA-loaded LMGO based nanoemulsion was prepared by a low energy technique, emulsion inversion point . The beaker containing an oil and surfactant mixture of CremophorELP and TranscutolP (1:1) was added with FA (1%) under continuous magnetic stirring.…”

“…19 The FA-loaded LMGO based nanoemulsion was prepared by a low energy technique, emulsion inversion point. 20 The beaker containing an oil and surfactant mixture of CremophorELP and TranscutolP (1:1) was added with FA (1%) under continuous magnetic stirring. The resultant mixture was finally microtitrated with water and labeled as FLMGO with FA and LMGO without FA.…”

Clinical Advances in Triple Negative Breast Cancer Treatment: Focus on Poly (L-lactide-coglycolide) Nanoparticles

“…This section specifically highlights the advancements in PLGA formulations for TNBC treatment (Tang et al, 2017;Parodi et al, 2022). Some problems and solutions associated with cargo delivery are that (1) many chemotherapy drugs are hydrophobic and have poor solubility, leading to challenges in their delivery, whereas encapsulation of nanoparticles, especially liposomes or micelles, can improve solubility and stability, enhancing drug delivery to target sites; (2) small inhibitors usually face rapid clearance and insufficient accumulation at the target site, whereas incorporating small inhibitors into nanoparticles can prolong circulation time and enhance their accumulation in tumor tissues through the enhanced permeability and retention (EPR) effect; (3) naked siRNA/miRNA face rapid degradation and poor cellular uptake, whereas nanoparticles offer protection to siRNA/miRNA, improve stability, and aid in targeted delivery, as well as facilitate endosomal escape, which overcomes a major hurdle in the intracellular delivery of nucleic acids (Tang et al, 2017;Chiang et al, 2021;Camorani et al, 2022;Parodi et al, 2022;Zare et al, 2022;Dinakar et al, 2023;Yusuf et al, 2023).…”