Thyroid Cancer in Isfahan Province, Iran; Prevalence and Demographic Characteristics

Abstract

Background: Previous studies confirm that thyroid cancer, as the most common endocrine cancer, accounts for about 1% of new malignant diseases all over the world. Objectives: As thyroid cancer incidence in Iran has changed rapidly over the past years, therefore this study was designed to investigate period prevalence (PP) and incidence rate (Irs.) of thyroid cancer in Isfahan Province, Iran. Methods: Recorded data of thyroid cancer were obtained from the Isfahan Cancer Registry at the Deputy of Health. Continuous variables were reported as means ± SD and categorical variables as frequencies and percentages. In order to examine the relationship of PP with age and gender, the t-test and chi-squared test were used, respectively. The PP was defined as the proportion of the total cases over the study years to the population at risk during the same period ×100000. Results: 1545 patients were diagnosed with thyroid cancer, among which 3% were related to death events. The mean (± SD) age of the study subjects was 41.9 ± 15.4 years. For the total population, the PP was calculated as 31.0, accounting for 49.3 versus 13.3 per 100000 for females versus males (P < 0.001). The study of Irs. data showed an increasing trend (P < 0.001) in the number of patients from 2011 to 2015. With a minimum age of three-years-old, in 84% of the patients, the age ranged from 20 to 60 years old. Conclusions: In this study, not only was the period prevalence 3.7 times higher in females than in males but also there was an increase (61.9%) in the incidence of thyroid cancer from the year 2011 to 2015. Based on the findings, however, detection methods of thyroid cancer have improved recently all over of the world, but a well-established classification of the disorder, pharmacotherapy, and surgical plan in the Iranian population can improve the clinical outcome. Further study in these contexts seem to be useful in Isfahan, Iran.

Cancers of Urinary System; Prevalence, Demographic

“…The results of this study showed that urinary bladder, kidney cancer followed an increasing trend in incidence, mortality and prevalence in Isfahan, Iran (14)(15)(16)(17)(18)(19)(20)(26)(27)(28)(29)(30)(31)(32). The implications of this investigation could be mentioned as the following suggestions: (1) the health care system should provide a model-based strategy to improve access to specialized medical, pharmacological and surgical facilities; (2) consideration is needed toward the reality for scheduling health system improvements, particularly referral systems; (3) preventing significant difficulties by equality of management for patient satisfaction; (4) attention toward financial management by study of epidemiology and pharmacotherapy.…”

Associated Complications and survival rate after thyroid cancer operation

“…We found that below 55 years old comprising (84.0%) of the total sample. According to previous literature, the occurrence of TC is considered to be much more in the age below 55 years old ,like what Ghamari (2019) published [18]. The explanation of young age group involvement in TC may be due to poor diet or iodine deficiencies in our environment.…”

Immunohistochemical Detection of Latent membrane Protein 1 and Human Twist Protein in Patients with Thyroid Cancer

“…Concerning the age distribution of the present study, it is observed that most of the patients with thyroid carcinoma have the age range of (20-60) years, these results are in accordance with the studies of other researchers Calangiu et al (2014). Who found the most positive case is in age group more than 45 years, through analysis of clinicopathological parameters of the 43 thyroids differentiated carcinomas and Ghamari (2019) show an increasing trend in the number of patients recently with a minimum age of three-years-old, in 84% of the patients, the age ranged from 20 to 60 years old in Iran.…”