Thyroid lobectomy for treatment of well differentiated intrathyroid malignancy

Nixon, Iain J.; Ganly, Ian; Patel, Snehal G.; Palmer, Frank L.; Whitcher, Monica M.; Tuttle, R. Michael; Shaha, Ashok; Shah, Jatin P.

doi:10.1016/j.surg.2011.08.016

Cited by 292 publications

(204 citation statements)

References 17 publications

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“…Similar findings were reported by Memorial Sloan Kettering in a matched pair analysis [20]. Single institutions would provide increasingly compelling evidence that more aggressive therapy was not associated with improved outcome [21][22][23][24]. These findings were supported by updated national database studies, which also concluded that a more aggressive approach could not be supported in low-risk groups [25].…”

Section: Prace Poglądowesupporting

confidence: 64%

“…Although injury rates are low in the hands of highvolume surgeons, this is not true for surgeons with less experience. However, those patients who have a lobectomy do require monitoring of the contralateral lobe, and around 10% of patients will require subsequent completion thyroidectomy if this approach is selected [23]. However, it is important to remember that this means that 90% of patients will not require completion thyroidectomy.…”

Section: Prace Poglądowementioning

confidence: 99%

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Wysoko zróżnicowany rak tarczycy — czy nie leczysz swoich pacjentów zbyt intensywnie?

Nixon

2016

Endokrynologia Polska

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Over the last 50 years there has been a move towards more aggressive therapy for well-differentiated thyroid cancer. In recent times, however, international guidelines have shown some trend back towards a more conservative approach to treating low-risk patients. This review explores how the state of the art in well-differentiated thyroid cancer research has evolved in tandem with improvements in riskstratification. A focus on the surgical approach to the primary thyroid tumour and the regional lymphatics in addition to the interplay between surgical decision making and the use of radioactive iodine are presented to allow the reader to determine whether they are now overtreating patients with well-differentiated thyroid cancer. StreszczenieW ciągu ostatnich 50 lat nastąpiła zmiana w leczeniu wysoko zróżnicowanego raka tarczycy na rzecz bardziej agresywnej terapii. Jednakże, całkiem niedawno, międzynarodowe wytyczne wskazały trend w kierunku powrotu ku bardziej konserwatywnemu podejściu w leczeniu pacjentów niskiego ryzyka. W niniejszym artykule opisano jak najnowsze badania na temat wysoko zróżnicowanego raka tarczycy ewoluują równocześnie z ulepszeniami w stratyfikacji ryzyka. Podejście chirurgiczne do raka pierwotnego tarczycy oraz regionalnych węzłów chłonnych przedstawiono wraz ze wzajemnymi zależnościami operacyjnego procesu decyzyjnego i wykorzystaniem radiojodu, aby umożliwić czytelnikowi ustalenie, czy zbyt intensywnie leczy pacjentów z wysoko zróżnicowanym rakiem tarczycy.

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Section: Prace Poglądowesupporting

confidence: 64%

Section: Prace Poglądowementioning

confidence: 99%

Wysoko zróżnicowany rak tarczycy — czy nie leczysz swoich pacjentów zbyt intensywnie?

Nixon

2016

Endokrynologia Polska

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“…However, several recent studies showed no significant difference in either disease-free survival or recurrence rate in patients with WDTC >1 cm after lobectomy versus TT (4,8). A recent reanalysis of the National Cancer Database of 61,775 patients showed that the extent of surgery was not associated with survival (3).…”

Section: Discussionmentioning

confidence: 99%

“…Total thyroidectomy (TT) has traditionally been recommended for thyroid cancers >1 cm (1,2). Several recent publications, however, have suggested that the extent of thyroidectomy-specifically, TT versus unilateral thyroid lobectomy-may not lead to significant differences in longterm outcomes for patients with WDTC up to 4 cm in size, likely because of the indolent nature of the majority of these tumors (3,4). Based on these data, recent guidelines for the management of WDTC have proposed thyroid lobectomy as an adequate surgical treatment for WDTC 1-4 cm in size in the absence of certain high-risk characteristics (5,6).…”

Section: Introductionmentioning

confidence: 99%

Frequency of High-Risk Characteristics Requiring Total Thyroidectomy for 1–4 cm Well-Differentiated Thyroid Cancer

Kluijfhout

Pasternak

Lim

et al. 2016

Thyroid

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“…Препаратом выбора является лево-тироксин [1, 2, [138][139][140][141][142][143][144][145][146][147][148][149][150][151][152].…”

Section: терапия левотироксиномunclassified

2016 Russian clinical practice guidelines for differentiated thyroid cancer diagnosis and treatment

et al. 2017

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В представленных клинических рекомендациях обсуждаются современные подходы к диагностике и лечению дифференцированного рака щитовидной железы у взрослых. Изменения в настоящей редакции Клинических рекомендаций касаются показаний к пункционной биопсии, скринингового определения концентрации кальцитонина, унификации заключений цитологического исследования, новых подходах к послеоперационной динамической стратификации риска рецидива, показаний к супрессивной и заместительной терапии, таргетной терапии йоднегативных форм дифференцированного рака щитовидной железы.

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Thyroid lobectomy for treatment of well differentiated intrathyroid malignancy

Cited by 292 publications

References 17 publications

Wysoko zróżnicowany rak tarczycy — czy nie leczysz swoich pacjentów zbyt intensywnie?

Wysoko zróżnicowany rak tarczycy — czy nie leczysz swoich pacjentów zbyt intensywnie?

Frequency of High-Risk Characteristics Requiring Total Thyroidectomy for 1–4 cm Well-Differentiated Thyroid Cancer

2016 Russian clinical practice guidelines for differentiated thyroid cancer diagnosis and treatment

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