Thyroidal response following iodine excess for cardiac catheterisation and intervention in early infancy

Dechant, Markus-Johann; Werf-Grohmann, Natascha van der; Neumann, E; Spiekerkoetter, Ute; Stiller, Brigitte; Grohmann, Jochen

doi:10.1016/j.ijcard.2016.08.292

Cited by 9 publications

(9 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…191 The authors suggest that the infants in this study could maintain euthyroidism via initiation and then successful escape from the Wolff−Chaikoff effect. In infants exposed to excess iodine during medical procedures, 74 despite application of iodine contrast media at an extremely high dose, no permanent thyroid dysfunction was observed.…”

Section: Vulnerable Groupsmentioning

confidence: 93%

“…Amiodarone, an antiarrhythmic drug, liberates 7−21 mg iodide daily depending on dosage . Povidone, iodine skin disinfectant, may be toxic to burn patients and neonates, the use of iodine‐containing preparations in neonates being particularly critical (see below) . Iodine‐containing contrast media can contain up to 370 mg/mL and is a common clinical source of excess iodine exposure .…”

Section: Potential Sources Of Excessive Iodine Exposurementioning

confidence: 99%

“…73 Povidone, iodine skin disinfectant, may be toxic to burn patients and neonates, 7 the use of iodine-containing preparations in neonates being particularly critical (see below). 74 Iodine-containing contrast media can contain up to 370 mg/mL and is a common clinical source of excess iodine exposure. 75 Large doses of iodine are also used in response to nuclear emergencies to reduce the uptake of radioiodines into the thyroid; 76 however, this particular use is beyond the scope of our review.…”

Section: Dietary Supplementsmentioning

confidence: 99%

See 2 more Smart Citations

Excess iodine intake: sources, assessment, and effects on thyroid function

Farebrother

Zimmermann

Andersson

2019

Annals of the New York Academy of Sciences

206

131

View full text Add to dashboard Cite

Iodine is essential for thyroid hormone synthesis. High iodine intakes are well tolerated by most healthy individuals, but in some people, excess iodine intakes may precipitate hyperthyroidism, hypothyroidism, goiter, and/or thyroid autoimmunity. Individuals with preexisting thyroid disease or those previously exposed to iodine deficiency may be more susceptible to thyroid disorders due to an increase in iodine intake, in some cases at intakes only slightly above physiological needs. Thyroid dysfunction due to excess iodine intake is usually mild and transient, but iodine‐induced hyperthyroidism can be life‐threatening in some individuals. At the population level, excess iodine intakes may arise from consumption of overiodized salt, drinking water, animal milk rich in iodine, certain seaweeds, iodine‐containing dietary supplements, and from a combination of these sources. The median urinary iodine concentration (UIC) of a population reflects the total iodine intake from all sources and can accurately identify populations with excessive iodine intakes. Our review describes the association between excess iodine intake and thyroid function. We outline potential sources of excess iodine intake and the physiological responses and consequences of excess iodine intakes. We provide guidance on choice of biomarkers to assess iodine intake, with an emphasis on the UIC and thyroglobulin.

show abstract

Section: Vulnerable Groupsmentioning

confidence: 93%

Section: Potential Sources Of Excessive Iodine Exposurementioning

confidence: 99%

Section: Dietary Supplementsmentioning

confidence: 99%

See 1 more Smart Citation

Excess iodine intake: sources, assessment, and effects on thyroid function

Farebrother

Zimmermann

Andersson

2019

Annals of the New York Academy of Sciences

206

131

View full text Add to dashboard Cite

show abstract

“…Screening for other thyroid‐related risk factors as autonomous thyroid and thyroid cancer follows the same pattern and half of the respondents reported that patients are not being checked for any of the mentioned thyroid conditions, while some of the respondents have no knowledge of whether the patients are screened for any thyroid condition (Figure 1). There is no consensus regarding the effect of ICM on children 9,15,16 and international guidelines 1,2 only recommend adjusting ICM doses to age and weight without mentioning thyroid effect. None of the respondents mentioned children among the patient groups they screen for thyroid conditions either.…”

Section: Discussionmentioning

confidence: 99%

“…Administration of ICM to children requires special caution. Some studies show increased risk of iodine‐induced thyroid dysfunction in children compared to adults and recommend monitoring of thyroid function particularly during the first year after exposure 9 while others claim that alteration of thyroid function after ICM administration is transient in most children 15,16 …”

Section: Introductionmentioning

confidence: 99%

Iodinated contrast media and their effect on thyroid function – Routines and practices among diagnostic imaging departments in Norway

Rusandu

Sjøvold

Hofstad

et al. 2020

J of Medical Radiation Sci

View full text Add to dashboard Cite

Introduction: In order to minimise adverse effects or patient injuries related to the effect of iodinated contrast media (ICM) on the thyroid, international guidelines and research recommend developing routines for identification and management of patients at risk of developing a thyroid dysfunction. This study aimed to investigate thyroid-related ICM administration practices among diagnostic imaging departments in Norway. Methods: The cross-sectional survey included 24 hospitals and 75 respondents with a 69% response rate. The survey covered practices for assessment and management of at-risk patients and the participants' perceived rationale for the routines. Results: The use of written checklists as recommended by international guidelines was quite modest (15%) and the respondents preferred various methods to identify risk and contraindications. Only 20% reported checking for any scheduled thyroidscintigraphy and/or radioactive-iodine therapy. 42% indicated that they did not have thyroid-related ICM routines, and the main perceived reason was lack of knowledge on the topic. Radiographers and radiologists expressed uncertainty about each other's roles and routines. Conclusion: This study revealed the need of optimisation of routines regarding ICM administration to patients at risk for thyroid dysfunction.

show abstract