THz spectroscopic characterization of biomolecule/water systems by compact sensor chips

Abstract

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THz wave propagation on strip lines: Devices, properties, and applications

“…In particular, we show that, by the use of low-permittivity dielectric materials, they can support the propagation of electrical pulses whose spectra reaching 3 THz for a distance as long as 1 mm. As an application of these devices, also we demonstrate the THz spectroscopic characterization of liquid and powder specimens [11][12][13]. In addition, we show that even lower attenuation can be realized in quadrupole mode in threestrip CPS (TSCPS) on low permittivity substrate.…”

“…Fig. 6 is the change in the attenuation with the immersion of bovine-serum-albumin (BSA) molecules at various densities [12]. With the increase of the density, the attenuation decreases because of the capturing of the free water molecules due to the hydration of albumin molecules.…”

Terahertz Emitters, Detectors and Sensors: Current Status and Future Prospects

“…Kitagawa et al [Kitagawa et al , 2006] demonstrated the THz spectroscopic performance of highly integrated sensor chips based on microstrip lines by measuring biomolecule/water systems. The concentration resolution of the chips reaches down to 0.05 g/ml.…”

A Novel Terahertz Sensing Device Comprising of a Parabolic Reflective Surface and a Bi-Conical Structure

“…The noise figure of THz detector by photoconductive antenna is high, so that a high signal to noise ratio (SNR) is required to extract the THz signal from the signal received. Parabolic mirrors have been widely used in THz systems to focus the weak THz power to the sample to increase the SNR [1][2][3][4][5][6]. On the other hand, a bi-conical structure has been widely used as a broadband radiation device with very high field concentration at gaps between the conical structure [12,13].…”

“…Terahertz (THz) sensing technology has received considerable attention in recent years for its potential applications in the detection of biological materials, skin cancer and spectral signature for molecular vibrations in RNA, DNA strands or proteins [1][2][3][4][5][6][7].…”