Time-resolved fluorescence and chemometrics-assisted excitation–emission fluorescence for qualitative and quantitative analysis of scopoletin and scopolin in Erycibe obtusifolia Benth

Li, Shipeng; Li, Xinge; Wang, Ji-Ye; Liu, Delong; Wei, Yongju

doi:10.1016/j.saa.2019.04.019

Cited by 15 publications

(2 citation statements)

References 19 publications

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“…For example, Wen et al (2015) established the HPLC fingerprint method for Erycibes plants to evaluate different batches' similarity according to the “SOP of the similarity evaluation system for the chromatographic fingerprint of TCM 2004 edition.” This method is accurate and straightforward, with good repeatability. Also, time‐resolved fluorescence and chemometrics‐assisted excitation–emission matrix fluorescence have been used for the qualitative and quantitative analysis of scopoletin and scopolin in E. obtusifolia (Liu et al, 2019). This strategy provides a suitable alternative to the chromatography‐based method.…”

Section: Quality Control Of Erycibes Plantsmentioning

confidence: 99%

Chemical compositions, pharmacological activities, quality control studies of Erycibes plants, and the development of their substitutes

Peng

Tao

Yang³

et al. 2021

Phytotherapy Research

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Erycibes are members of the Convolvulaceae family, including more than 10 species worldwide that are distributed in tropical Asia. Some Erycibes species have long been used as traditional remedies for rheumatoid arthritis, fever, hepatitis, and liver injury in China and Thailand. A total of 152 compounds from Erycibes plants have been isolated and identified, categorized as flavonoids, coumarins, quinic acid derivatives, lignans, and alkaloids. Coumarins are the characteristic and active constituents of this species, including scopoletin and scopolin. Modern pharmacological studies have shown that the extracts and bioactive components of Erycibes plants exhibit several biological activities, including antiinflammatory, analgesic, hepatoprotective, anti‐gout, antitumor, antioxidation, and other therapeutic effects. However, in recent years, due to destructive exploitation and utilization, some Erycibes plants' natural resources have become rare or endangered. Developing substitutes is a strategy to alleviate the pressure on those endangered medicinal plant resources. To provide a scientific basis for the development and protection of those threatened Erycibes species, this review summarized the current status of the chemical compositions, pharmacological activities, quality control studies, and the development of substitutes for Erycibes plants. In particular, the rationale for use of Porana sinensis currently on the market is discussed.

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Section: Quality Control Of Erycibes Plantsmentioning

confidence: 99%

Chemical compositions, pharmacological activities, quality control studies of Erycibes plants, and the development of their substitutes

Peng

Tao

Yang³

et al. 2021

Phytotherapy Research

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“…Among these methods, EEM spectroscopy has the advantages of rapidity, simplicity, low cost, high sensitivity, and non-destructiveness. At present, a large number of reports on the analysis of ingredients in foods and medicines by fluorescence spectroscopy combined with chemometrics methods have been reported, and a few examples include those of Bai et al ( 2018 ), Liu et al ( 2019 ), Wang et al ( 2017 ), and Li et al ( 2021 ). These successful examples demonstrated that fluorescence spectroscopy combined with chemometrics methods can be regarded as an effective way to quantitatively analyze target components in complex systems.…”

Section: Introductionmentioning

confidence: 99%

A comparative study of three chemometrics methods combined with excitation–emission matrix fluorescence for quantification of the bioactive compounds aesculin and aesculetin in Cortex Fraxini

Lin

et al. 2022

Front. Chem.

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Cortex Fraxini is an important traditional Chinese herbal medicine with various medical functions. Aesculin and aesculetin are the main effective components of Cortex Fraxini. The fluorescence signals of the two compounds have a high degree of overlap with each other, making quantitative analysis difficult with conventional analytical methods. In the present study, different chemometrics methods, including lasso regression (LAR), interval partial least squares (iPLS), and multidimensional partial least squares (N-PLS) methods, were employed and combined with excitation–emission matrix (EEM) fluorescence for the purpose of accurate quantification of aesculin and aesculetin in Cortex Fraxini samples. The most satisfactory results were obtained by using the N-PLS method based on the EEM spectra without scatterings, with correlation coefficient of calibration and prediction values higher than 0.9972 and 0.9962, respectively, root mean squared errors for calibration and prediction values lower than 0.0304 and 0.1165, respectively, and recovery values in the range of 83.32%–104.62%. The obtained credible models indicated that the N-PLS method combined with EEM spectra has the advantages of being green, low cost, and accurate and it is a good strategy for the determination of active compounds in complex samples. To further confirm the accuracy of the obtained results, the same samples were analyzed by the recognized ultra-performance liquid chromatography method.

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HPLC and HPLC–MS for Qualitative and Quantitative Analysis of Chinese Medicines

Qin,

Li,

Zhao

2024

Quality Control of Chinese Medicines

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Time-resolved fluorescence and chemometrics-assisted excitation–emission fluorescence for qualitative and quantitative analysis of scopoletin and scopolin in Erycibe obtusifolia Benth

Cited by 15 publications

References 19 publications

Chemical compositions, pharmacological activities, quality control studies of Erycibes plants, and the development of their substitutes

Chemical compositions, pharmacological activities, quality control studies of Erycibes plants, and the development of their substitutes

A comparative study of three chemometrics methods combined with excitation–emission matrix fluorescence for quantification of the bioactive compounds aesculin and aesculetin in Cortex Fraxini

HPLC and HPLC–MS for Qualitative and Quantitative Analysis of Chinese Medicines

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