“…Previous investigations have found missed clinic appointments in HIV care to be associated with several critical impacts, including incomplete or protracted timeto-viral suppression (Crawford et al, 2014;Mugavero, Amico, et al, 2012;Sethi, Celentano, Gange, Moore, & Gallant, 2003), premature mortality (Brennan, Maskew, Sanne, & Fox, 2010;Zhang et al, 2012), and clinical therapy failure (Sullivan et al, 2011). Where the end point was mortality, therapy interruption explained the observation, but because HIV clinic-visit consistency is a structural constituent of engagement in care, other mediators may explain the nonmortality outcomes.…”