Time trends in mobile phone use and glioma incidence among males in the Nordic Countries, 1979–2016

Deltour, Isabelle; Poulsen, Aslak Harbo; Johansen, Christoffer; Feychting, Maria; Johannesen, Tom Børge; Auvinen, Anssi; Schüz, Joachim

doi:10.1016/j.envint.2022.107487

Cited by 12 publications

(4 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Due to the changing nature of exposure, monitoring of time trends of glioma incidence rates is important, with the most recent one not showing any change in time trends compatible with the hypothesis of an increased risk from mobile phone use. 16 …”

Section: Discussionmentioning

confidence: 99%

Effects of Recall and Selection Biases on Modeling Cancer Risk From Mobile Phone Use: Results From a Case–Control Simulation Study

Bouaoun,

Byrnes,

Lagorio

et al. 2024

Epidemiology

Self Cite

View full text Add to dashboard Cite

Background: The largest case–control study (Interphone Study) investigating glioma risk related to mobile phone use showed a J-shaped relationship with reduced relative risks for moderate use and a 40% increased relative risk among the 10% heaviest regular mobile phone users, using a categorical risk model based on deciles of lifetime duration of use among ever regular users. Methods: We conducted Monte-Carlo simulations examining whether the reported estimates are compatible with an assumption of no effect of mobile phone use on glioma risk when the various forms of biases present in the Interphone study are accounted for. Four scenarios of sources of error in self-reported mobile phone use were considered, along with selection bias. Input parameters used for simulations were those obtained from Interphone validation studies on reporting accuracy and from using a non-response questionnaire. Results: We found that the scenario simultaneously modeling systematic and random reporting errors produced a J-shaped relationship perfectly compatible with the observed relationship from the main Interphone study with a simulated spurious increased relative risk among heaviest users (OR = 1.91) compared to never regular users. The main determinant for producing this J shape was higher reporting error variance in cases compared to controls, as observed in the validation studies. Selection bias contributed to the reduced risks as well. Conclusions: Some uncertainty remains, but the evidence from the present simulation study shifts the overall assessment to making it less likely that heavy mobile phone use is causally related to an increased glioma risk.

show abstract

Section: Discussionmentioning

confidence: 99%

Effects of Recall and Selection Biases on Modeling Cancer Risk From Mobile Phone Use: Results From a Case–Control Simulation Study

Bouaoun,

Byrnes,

Lagorio

et al. 2024

Epidemiology

Self Cite

View full text Add to dashboard Cite

show abstract

“…The reported increase of brain cancer in mobile phone users before 2010 was the reason for the IARC’s 2B classification. If the increased risk ratios were correct, brain cancer would have increased in recent years, but this is not the case according to the clinical data [ 33 ]. The authors of [ 33 ] concluded: “Our findings indicate that glioma incidence trends among men aged 40–59 years in the Nordic countries are not consistent with increased risks of moderate effect size (RR > 1.2–1.4) assuming latency up to 20 years.…”

Section: Problems In Researchmentioning

confidence: 99%

“…If the increased risk ratios were correct, brain cancer would have increased in recent years, but this is not the case according to the clinical data [ 33 ]. The authors of [ 33 ] concluded: “Our findings indicate that glioma incidence trends among men aged 40–59 years in the Nordic countries are not consistent with increased risks of moderate effect size (RR > 1.2–1.4) assuming latency up to 20 years. This means that increased risks reported in some case-control studies are implausible and likely attributable to biases and errors in self-reported use of mobile phone”.…”

Section: Problems In Researchmentioning

confidence: 99%

Controversy in Electromagnetic Safety

Chou¹

2022

IJERPH

View full text Add to dashboard Cite

The dramatic increase in electromagnetic fields (EMFs) in the environment has led to public health concerns around the world. Based on over 70 years of research in this field, the World Health Organization (WHO) has concluded that scientific knowledge in this area is now more extensive than for most chemicals and that current evidence does not confirm the existence of any health consequences from exposure to low-level electromagnetic fields. However, controversy on electromagnetic safety continues. Two international groups, the International Committee on Electromagnetic Safety of the Institute of Electric and Electronics Engineers (IEEE) and the International Commission on Non-Ionizing Radiation Protection, have been addressing this issue for decades. While the goal of both groups is to provide human exposure limits that protect against established or substantiated adverse health effects, there are groups that advocate more stringent exposure limits, based on possible biological effects. Both biological and engineering complexities make the validity of many EMF studies questionable. Controversies in research, publication, standards, regulations and risk communication concerning electromagnetic safety will be addressed in this article. The WHO is conducting systematic reviews on the RF biological effects literature. If scientists would discuss the safety issues of EMFs based on validated scientific facts and not on unreproducible possible effects and opinions, the controversy would be minimized or resolved.

show abstract

“…The annual incidence of gliomas is approximately of six cases per 100,000 people [1], with a slight prevalence in men. While the majority of cases are sporadic, it is estimated that about 5% of gliomas show a hereditary component in rare tumor predisposition syndromes (Cowden's Syndrome, Turcot's Syndrome, Lynch's Syndrome, Li Fraumeni's Syndrome and Neurofibromatosis type I and II) [2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Surgical management of Glioma Grade 4: technical update from the neuro-oncology section of the Italian Society of Neurosurgery (SINch®): a systematic review

et al. 2023

View full text Add to dashboard Cite

Purpose The extent of resection (EOR) is an independent prognostic factor for overall survival (OS) in adult patients with Glioma Grade 4 (GG4). The aim of the neuro-oncology section of the Italian Society of Neurosurgery (SINch®) was to provide a general overview of the current trends and technical tools to reach this goal. Methods A systematic review was performed. The results were divided and ordered, by an expert team of surgeons, to assess the Class of Evidence (CE) and Strength of Recommendation (SR) of perioperative drugs management, imaging, surgery, intraoperative imaging, estimation of EOR, surgery at tumor progression and surgery in elderly patients. Results A total of 352 studies were identified, including 299 retrospective studies and 53 reviews/meta-analysis. The use of Dexamethasone and the avoidance of prophylaxis with anti-seizure medications reached a CE I and SR A. A preoperative imaging standard protocol was defined with CE II and SR B and usefulness of an early postoperative MRI, with CE II and SR B. The EOR was defined the strongest independent risk factor for both OS and tumor recurrence with CE II and SR B. For intraoperative imaging only the use of 5-ALA reached a CE II and SR B. The estimation of EOR was established to be fundamental in planning postoperative adjuvant treatments with CE II and SR B and the stereotactic image-guided brain biopsy to be the procedure of choice when an extensive surgical resection is not feasible (CE II and SR B). Conclusions A growing number of evidences evidence support the role of maximal safe resection as primary OS predictor in GG4 patients. The ongoing development of intraoperative techniques for a precise real-time identification of peritumoral functional pathways enables surgeons to maximize EOR minimizing the post-operative morbidity.

show abstract

Time trends in mobile phone use and glioma incidence among males in the Nordic Countries, 1979–2016

Cited by 12 publications

References 30 publications

Effects of Recall and Selection Biases on Modeling Cancer Risk From Mobile Phone Use: Results From a Case–Control Simulation Study

Effects of Recall and Selection Biases on Modeling Cancer Risk From Mobile Phone Use: Results From a Case–Control Simulation Study

Controversy in Electromagnetic Safety

Surgical management of Glioma Grade 4: technical update from the neuro-oncology section of the Italian Society of Neurosurgery (SINch®): a systematic review

Contact Info

Product

Resources

About