“…Besides genetic predisposition, several risk factors are suggested to play a role in the development and progression of CRC, such as obesity, smoking, and diet (Dai et al, 2007;Guh et al, 2009;Harriss et al, 2009;Johnson et al, 2013). Males are more likely to be addicted to drinking, smoking, and suffer from more living pressure, which may account for the relative high incidence of all kinds of cancer, including colorectal cancer (Morris et al, 1991;Weiderpass et al, 2006;Ibfelt et al, 2013;Levi et al, 2013;Menvielle et al, 2013;Parise et al, 2013;Manser et al, 2014). At present, some scientists say that people's educational background and socioeconomic status also play a role in the unbalanced distribution of colorectal cancer (Morris et al, 1991;Weiderpass et al, 2006;Parise et al, 2013).…”