Tinea Corporis Gladiatorum Presenting as a Majocchi Granuloma

Kurian, Anil; Haber, Richard M.

doi:10.5402/2011/767589

Cited by 18 publications

(13 citation statements)

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“…According to our experience and the literature research, it is advised to maintain a minimum of 8 weeks in the case of griseofulvin and 6-8 weeks in systemic azoles [13,[67][68][69] and treatment should be continued until all lesions are cleared. Gupta, in 1995 [71], reported the efficacy of terbinafine in the management of MG associated with fungi of the genus Trichophyton, with good antidermatophytic activity, adequate penetration to common sites of dermatophytes (stratum corneum and hair follicle), and reduction of the recurrence at 6 months and few side effects [16,30,72,73].…”

Section: Treatmentmentioning

confidence: 99%

Majocchi’s Granuloma (Dermatophytic Granuloma): Updated Therapeutic Options

Tirado‐Sánchez

Ponce-Olivera

Bonifáz

2015

Curr Fungal Infect Rep

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Majocchi's granuloma (MG) is a rare, well-recognized, deep skin infection caused by dermatophyte, which can be seen in immunosuppressed as well as immunocompetent individuals. It is primarily caused by dermatophytes, most commonly Trichophyton rubrum; however, occasionally other Trichophyton sp., Trichosporon sp., Aspergillus sp., and Phoma sp. are involved. Diagnosis is based on clinical, mycological, and histological characteristics. This review focuses on clinical characteristics of MG and diagnosis and therapeutic options of MG.

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Section: Treatmentmentioning

confidence: 99%

Majocchi’s Granuloma (Dermatophytic Granuloma): Updated Therapeutic Options

Tirado‐Sánchez

Ponce-Olivera

Bonifáz

2015

Curr Fungal Infect Rep

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“…In most cases of Majocchi granuloma, T. rubrum is the causal pathogen, but other dermatophytes have also been described, e.g. T. tonsurans as pathogen of tinea corporis gladiatorum clinically presenting as Majocchi granuloma .…”

Section: Clinical Picture Of Dermatomycosesmentioning

confidence: 99%

Mycology – an update Part 2: Dermatomycoses: Clinical picture and diagnostics

Nenoff¹,

Krüger²,

Schaller

et al. 2014

J Deutsche Derma Gesell

100

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Summary Most fungal infections of the skin are caused by dermatophytes, both in Germany and globally. Tinea pedis is the most frequent fungal infection in Western industrial countries. Tinea pedis frequently leads to tinea unguium, while in the elderly, both may then spread causing tinea corporis. A variety of body sites may be affected, including tinea glutealis, tinea faciei and tinea capitis. The latter rarely occurs in adults, but is the most frequent fungal infection in childhood. Following antifungal treatment of tinea unguium and also tinea capitis a dermatophytid or hyperergic reaction to dermatophyte antigens may occur. Yeast infections affect the mucous membranes both of the gastro‐intestinal system and the genital tract as candidiasis mostly due to Candida albicans. Cutaneous candidiasis affects predominantely the intertriginous regions such as groins and the inframammary area, but also the intertriginous space of fingers and toes. In contrast, pityriasis versicolor is a superficial epidermal fungal infection primarily on the the trunk. Mold infections are rare in dermatology; they play a role nearly exclusively in nondermatophyte‐mold (NDM) onychomycosis. The diagnosis of dermatomycoses comprises the microscopic detection of fungi using the potassium hydroxide preparation or alternatively the fluorescence optical Blankophor preparation together with culture. The histological fungal detection with PAS staining possesses a high sensitivity, and it should play a more important role in particular for diagnosis of onychomycosis. Molecular biological methods, based on the amplification of fungal DNA with use of specific primers for the distinct causative agents are on the rise. With PCR, such as dermatophyte‐PCR‐ELISA, fungi can be detected directly in clinical material in a highly specific and sensitive manner without prior culture. Today, molecular methods, such as Matrix Assisted Laser Desorption/Ionization Time‐Of‐Flight Mass Spectrometry (MALDI TOF MS) as culture confirmation assay, complete the conventional mycological diagnostics.

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“…El diagnóstico se basa en la integración de exámenes directos con KOH, cultivo para hongos, intradermorreacción específica a la tricofitina; aunque la prueba confirmatoria es el estudio histopatológico por microscopia de luz (20,21). En esta enfermedad se observa foliculitis supurativa profunda y granulomatosa con infiltrado de linfocitos, macrófagos, células epitelioides y células gigantes.…”

Section: Discussionunclassified

Granuloma de Majocchi: una forma de infección dermatofítica invasiva

R.¹,

Sañudo²,

Calle³

et al. 2017

CES Med.

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Comparte ResumenEl granuloma de Majocchi es una forma de infección atípica por dermatofitos con invasión de la dermis y el tejido celular subcutáneo, favorecida por el trauma de los folículos pilosos o la inmunosupresión del huésped. Siendo una infección poco común, se destaca en este artículo el caso de una paciente que luego de usar esteroides tópicos presentó pápulas y pústulas en vulva, sitio inusual de granuloma de Majocchi, siendo este el cuarto reporte a nivel mundial.Palabras clave: Granuloma, Dermatofitos, Foliculitis, Majochi. AbstractMajocchi granuloma is a form of atypical infection by dermatophytes with invasion of the dermis and subcutaneous tissue, favored by the trauma of hair follicles or host immunosuppression. Being a rare infection, in this article highlights the case of a patient with papules and pustules on the vulva after using topical steroids, an unusual site Majocchi granuloma, which is the fourth global report.Keywords: Granuloma, Dermatophytes, Folliculitis, Majochi. IntroducciónLos dermatofitos comprenden tres géneros: Epidermophyton, Trichophyton y Microsporum. Son queratinofílicos en humanos y animales y están usualmente restringidos a capas cornificadas de la epidermis, sin invadir más allá de ella (1). En un huésped inmunocompetente son incapaces de penetrar tejidos viables, pero bajo condiciones de inmunosupresión adquieren la habilidad de invadir la dermis y diseminarse a nivel sistémico. Existen cuatro formas de infecciones invasivas de dermatofitos: el granuloma de Majocchi, la dermatofitosis profunda, la diseminada, y el micetoma o pseudomicetoma por dermatofitos (2). Caso clínicoSe trataba de una paciente de 14 años quien consultó a un hospital local por un cuadro de un mes de evolución que consistía en pápulas eritematosas, vesículas y pústulas en la piel del abdomen, del cual se hizo un diagnóstico inicial de eccema y se ordenaron esteroides tópicos. Posteriormente, las lesiones se extendieron hacia la vulva y región inguinal izquierda, por lo que fue remitida a un hospital de la ciudad.

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Tinea Corporis Gladiatorum Presenting as a Majocchi Granuloma

Cited by 18 publications

References 9 publications

Majocchi’s Granuloma (Dermatophytic Granuloma): Updated Therapeutic Options

Majocchi’s Granuloma (Dermatophytic Granuloma): Updated Therapeutic Options

Mycology – an update Part 2: Dermatomycoses: Clinical picture and diagnostics

Granuloma de Majocchi: una forma de infección dermatofítica invasiva

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