Tinnitus Does Not Interfere with Auditory and Speech Perception

Zeng, Fan‐Gang; Richardson, Matthew; Turner, Katie

doi:10.1523/jneurosci.0396-20.2020

Cited by 49 publications

(63 citation statements)

References 91 publications

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“…The present findings are not consistent with Zeng et al 17 , who found no significant difference in utilization of talker sex cues to segregate competing speech between tinnitus and non-tinnitus listeners. Differences in test materials and methods may partly explain discrepancies between studies.…”

Section: Resultscontrasting

confidence: 99%

“…For multi-talker babble, masking is reduced as the number of talkers increase beyond 2 33 – 35 . Previous speech perception studies in tinnitus listeners have involved steady noise 17 , multi-talker babble 7 , 22 , 36 and 1 competing talker 17 . Kidd et al 37 found large masking release (MR) due to the difference in talker sex cues and/or spatial cues, which is primarily driven by the reduction in the informational masking, especially with 2-talker competing maskers.…”

Section: Introductionmentioning

confidence: 99%

“…Compared to NH listeners without tinnitus, some previous studies show perceptual deficits in NH listeners with tinnitus for a variety of basic auditory discrimination measures (e.g., gap detection, duration discrimination, frequency discrimination, low-frequency amplitude modulation (AM) detection, intensity discrimination) [7][8][9][10][11][12][13][14] . However, other studies have shown no differences between tinnitus and non-tinnitus listeners for other auditory measures (e.g., gap detection, intensity discrimination, high-frequency AM detection, spectral ripple discrimination, Schroeder-phase discrimination) [15][16][17][18] .…”

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confidence: 99%

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Tinnitus impairs segregation of competing speech in normal-hearing listeners

Liu

Wang

Chen

et al. 2020

Sci Rep

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Many tinnitus patients report difficulties understanding speech in noise or competing talkers, despite having “normal” hearing in terms of audiometric thresholds. The interference caused by tinnitus is more likely central in origin. Release from informational masking (more central in origin) produced by competing speech may further illuminate central interference due to tinnitus. In the present study, masked speech understanding was measured in normal hearing listeners with or without tinnitus. Speech recognition thresholds were measured for target speech in the presence of multi-talker babble or competing speech. For competing speech, speech recognition thresholds were measured for different cue conditions (i.e., with and without target-masker sex differences and/or with and without spatial cues). The present data suggest that tinnitus negatively affected masked speech recognition even in individuals with no measurable hearing loss. Tinnitus severity appeared to especially limit listeners’ ability to segregate competing speech using talker sex differences. The data suggest that increased informational masking via lexical interference may tax tinnitus patients’ central auditory processing resources.

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Section: Resultscontrasting

confidence: 99%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

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Tinnitus impairs segregation of competing speech in normal-hearing listeners

Liu

Wang

Chen

et al. 2020

Sci Rep

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“…Such studies have shown that participants with tinnitus are able to detect gaps of silence in a background noise (Campolo et al, 2013;Boyen et al, 2015), thus invalidating the original hypothesis developed in rats (Turner et al, 2006). These results may be explained by a recent study which found that tinnitus is perceived as separate from external sounds, thus not interfering with gap detection (Zeng et al, 2020). However, some reports have suggested that gap detection differences can be identified in patients with tinnitus when assessed with cortical evoked potentials (Mahmoudian et al, 2013(Mahmoudian et al, , 2015Paul et al, 2018).…”

Section: Limitations Of the Asr And Abr Methodologymentioning

confidence: 97%

A Novel Mouse Model of Aminoglycoside-Induced Hyperacusis and Tinnitus

Longenecker¹,

Gu²,

Homan³

et al. 2020

Front. Neurosci.

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Aminoglycosides (AG) such as amikacin are commonly used in cystic fibrosis patients with opportunistic pulmonary infections including multi-drug resistant mycobacterium tuberculous and non-tuberculous mycobacterium. Unfortunately, this class of drugs is known to cause peripheral damage to the cochlea leading to hearing loss that can fluctuate and become permanent over time or multiple exposures. However, whether amikacin can lead to central auditory dysfunction like hyperacusis (increased sensitivity to sound) or tinnitus (perception of sound in the absence of acoustic stimulation) is not well-described in the literature. Thus, an animal model needs to be developed that documents these side effects in order to develop therapeutic solutions to reduce AG-induced auditory dysfunction. Here we present pioneer work in mice which demonstrates that amikacin can lead to fluctuating behavioral evidence of hyperacusis and tinnitus as assessed by the acoustic startle reflex. Additionally, electrophysiological assessments of hearing via auditory brainstem response demonstrate increased central activity in the auditory brainstem. These data together suggest that peripheral AG-induced dysfunction can lead to central hyperactivity and possible behavioral manifestations of hyperacusis and tinnitus. Importantly, we demonstrate that ebselen, a novel investigational drug that acts as both an antioxidant and anti-inflammatory, can mitigate AG-induced hyperacusis.

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“…Furthermore, it has been shown that tinnitus reduction can improve speech perception (Mertens et al 2013), but we did not find this phenomenon in our study. Tinnitus itself seems to have a relationship with speech perception, but whether it improves or deteriorates speech perception is still unclear (Ivansic et al 2017;Jagoda et al 2018;Oosterloo, Homans, and Goedegebure 2020;Zeng, Richardson, and Turner 2020).…”

Section: Speech Perceptionmentioning

confidence: 99%

Sound therapy for cochlear implant users with tinnitus

Heteren

Arts

Killian

et al. 2020

International Journal of Audiology

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Objective: Despite the positive effect of a cochlear implant (CI) on tinnitus in many patients, tinnitus remains a problem for a significant proportion of CI users. We investigated the acceptability and effect of sound therapy (a combination of natural background sounds and one concise tinnitus counselling session) on tinnitus and speech perception in CI users who still experienced tinnitus during CI use. Design and study sample: Thirty-two CI users (32-78 years) participated in phase 1: a test at the clinic to evaluate six background sounds provided by the sound processor. Eighteen out of the 32 CI users participated in phase 2: an optional take-home evaluation of 2 weeks without sound therapy, followed by 5 weeks with sound therapy, ending with an evaluation visit. Results: Thirty subjects (93.8%) found at least one background sound acceptable. In phase 2, a small improvement with sound therapy was found for tinnitus loudness, annoyance, and intrusiveness. 50% of the subjects subjectively reported benefit of sound therapy. Especially the sense of control on their tinnitus was highly appreciated. No detrimental effect on speech perception was observed. Conclusion: The background sounds were acceptable and provided tinnitus relief in some CI users with tinnitus during CI use.

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Tinnitus Does Not Interfere with Auditory and Speech Perception

Cited by 49 publications

References 91 publications

Tinnitus impairs segregation of competing speech in normal-hearing listeners

Tinnitus impairs segregation of competing speech in normal-hearing listeners

A Novel Mouse Model of Aminoglycoside-Induced Hyperacusis and Tinnitus

Sound therapy for cochlear implant users with tinnitus

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