Tissue Adhesives and Alternative Wound Closure

Trott, Alexander T.

doi:10.1016/b978-0-323-07418-6.00014-9

Cited by 2 publications

(1 citation statement)

References 25 publications

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“…However, in our patient Escherichia coli are the cultured organism. This may be due to the fact that human bite infection by hospitalised or institutionalized patients are caused by gram-negative organisms such as Escherichia coli, Proteus and Pseudomonas [11]. The assailant in the case of our patient is a schizophrenic patient who has been in and out of psychiatric hospital severally.…”

Section: Discussionmentioning

confidence: 90%

Fatal Necrotising Soft Tissue Infection Following Human Bite; a Case Report and Review of Literature

Ibrahim

2014

BJMMR

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Human bite injuries are one of the commonest bite injuries seen in the emergency room in a developing country. This bite injury can occasionally lead to devastating complications but yet, one of the most neglected injuries by both the victims and inexperienced attending Clinician. We present a case of fatal and extensive necrotising fasciitis by Eschcerecia coli following human bite by a schizophrenic patient.

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Section: Discussionmentioning

confidence: 90%

Fatal Necrotising Soft Tissue Infection Following Human Bite; a Case Report and Review of Literature

Ibrahim

2014

BJMMR

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Functionalized Multiarmed Polycaprolactones as Biocompatible Tissue Adhesives

Zhang

Lyon

et al. 2020

ACS Appl. Mater. Interfaces

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Existing tissue adhesives have a trade-off between adhesive strength and biocompatibility. Here, we report a series of biocompatible multiarmed polycaprolactones (PCL) as tissue adhesives that can be released from a hot glue gun and the length of each arm was kept at ∼2–3 kg mol–1 in all the polymers. The adhesion properties were dependent on the number of functionalized (N-hydroxysuccinimide ester (NHS), aldehyde (CHO), and isocyanate (NCO)) arms of the multiarmed polymers. The more arms, the higher the adhesion strength. For example, the adhesion strength in binding cut rat skin increased from 2.3 N cm–2 for 2PCL-NHS to 11.2 N cm–2 for 8-PCL-NHS. CHO- and NCO-modified 8PCL also had suitable adhesive properties. All the multiarmed polymers had minimal cytotoxicity in vitro and good biocompatibility in vivo, suggesting their potential as promising alternative surgical adhesives.

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Tissue Adhesives and Alternative Wound Closure

Cited by 2 publications

References 25 publications

Fatal Necrotising Soft Tissue Infection Following Human Bite; a Case Report and Review of Literature

Fatal Necrotising Soft Tissue Infection Following Human Bite; a Case Report and Review of Literature

Functionalized Multiarmed Polycaprolactones as Biocompatible Tissue Adhesives

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