Tissue pO2 in Isometrically Contracting Skeletal Muscle of Rats with Portacaval Anastomosis (PCA)

ISFET and Fiber Optic Sensor Technologies: In Vivo Experience for Critical Care Monitoring

“…Presently, there are two systems commercially available for continuous in vivo monitoring of oxygenation of tissue beds. A highly engineered electrode system was developed and tested in other applications and optimized to monitor brain parenchyma, i.e., brain IF, PO 2 (Licox, Integra LifeSciences Inc., Plainsboro, NJ; www.integra-ls.com). ,,,, The system incorporates a precalibrated electrode PO 2 probe (0.8 mm diameter) and intraparenchyma placement system for use in monitoring brain oxygenation after injury during intensive care for time periods of days. Another technology, near-infrared spectrometry (NIRS), has been developed for noninvasively monitoring tissue hemoglobin O 2 saturation for time periods of days (Inspectra, Hutchinson Technology Inc., Hutchinson, MN; www.htbiomeasurement.com).…”