Titan-Prothesen im Mittelohr

Stupp, C. H.; Dalchow, Carsten V.; Grün, D.; Stupp, H.; Wustrow, J.

doi:10.1055/s-2007-996875

Cited by 49 publications

(17 citation statements)

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“…Extrusion rates in our study were comparable to those of Ho et al [13] (4%) and of Begall et al [10] (4.4%). Rates of revision surgery were higher compared to other studies by Stupp et al [11] (5.6%), Martin and Harner [15] (7%) and Gardner et al [14] (6%).…”

Section: Discussioncontrasting

confidence: 59%

“…A study done by Stupp et al [11,12] found a success rate of 76%, studies by Ho et al [13] and Gardner et al [14] have reported success rate of 56% (64% for PORP and 45% for TORP) and 71% for PORP and 44% for TORP respectively. In the present study success was considered after attaining dry ear and with a postoperative improvement of an Air Bone Gap of 20 dB or less and our success rate was 76.47% (75% for PORP and 77.77% for TORP).…”

Section: Discussionmentioning

confidence: 96%

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Preliminary Hearing Results of Tympanomastoidectomies Using Titanium Prostheses: Scenario in a Developing Country

Sayal¹,

Taneja²,

Gulati³

2013

IJOHNS

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The study was done to review postoperative hearing gain of patients with different Middle Ear Risk Index (MERI) undergoing Tympanomastoidectomies with titanium prostheses reconstruction. A Retrospective chart review was performed from September 2009 to December 2011. Of the 17 cases, 9 had moderate MERI while 8 had severe MERI. 9 patients underwent Tympanomastoidectomy with Total Ossicular Reconstruction Prostheses (TORP) and 8 with Partial Ossicular Reconstruction Prostheses (PORP). Hearing gain of 25.31 dB was achieved in cases with moderate MERI compared to 29.37 dB in severe MERI. Less than 20 dB average air-bone gap was achieved in 75% of PORP and 77.77% of TORP reconstructions. In developing countries with limited resources, decision regarding ossicular reconstruction should be made taking into account MERI, intra operative findings and type of surgery. Best results are achieved in cases of CWD with TORP and ICW with PORP.

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Section: Discussioncontrasting

confidence: 59%

Section: Discussionmentioning

confidence: 96%

Preliminary Hearing Results of Tympanomastoidectomies Using Titanium Prostheses: Scenario in a Developing Country

Sayal¹,

Taneja²,

Gulati³

2013

IJOHNS

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“…Nowadays, in some ear specialists' opinion, long-term follow-ups may even reach up to 20% of extrusion-related failures. Recently, both hydroxylapatite (HA), due to its chemical similarity to the mineral phase of the osseous tissue (Grote et al 1981;Grote 1986;Wehrs 1995;Goldenberg and Driver 2000;Rondini-Gilli et al 2003) and, more recently, titanium (Ti) (Stupp et al 1999;Zenner et al 2001;Ho et al 2003;Gardner et al 2004;Martin and Harner 2004), due to its processability in minute shape and its success as bone substitute, are the most commonly used biomaterials for ossicular prostheses.…”

Section: Introductionmentioning

confidence: 99%

Novel biological/biohybrid prostheses for the ossicular chain: fabrication feasibility and preliminary functional characterization

Danti

Stefanini

D’Alessandro

et al. 2009

Biomed Microdevices

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Alternatives for ossicular replacements were fabricated in order to overcome persisting rejections in middle ear prosthetization. Unlike the synthetic prostheses in fashion, we propose biological and biohybrid replacements containing extra cellular matrix (ECM) molecules to improve biointegration. In this study, ECM-containing devices shaped as Partial Ossicular Replacement Prostheses (PORPs) were fabricated reproducing the current synthetic models. Biological PORPs were obtained from human decellularized cortical bone allografts by computer numerically controlled ultraprecision micromilling. Moreover, porous PORP-like scaffolds were produced and cultured with osteoinduced human mesenchymal stromal cells to generate in vitro bone ECM within the scaffold porosity (biohybrid PORPs). The acoustic responses of such devices were investigated and compared to those of commercial prostheses. Results showed that biological PORPs transmit mechanical signals with appropriate frequencies, amplitudes, and with early extinction time. Although signal transmission in biohybrid PORPs showed insufficient amplitude, we believe that tissue engineered constructs represent the new challenge in ossiculoplasty.

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“…Die Vielzahl der verschiedenen Designvorschläge zeigt, dass die ideale Prothese bisher nicht gefun− den wurde. Bei weniger als 3/4 der Patienten ge− lingt es mithilfe dieser Rekonstruktionen, die postoperativ verbleibende Schallleitungskompo− nente auf 20 dB oder weniger zu reduzieren [5]. Ungeachtet …”

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Experimentelle Untersuchungen zu Mittelohrimplantaten mit integriertem mikromechanischem Gelenk

Beleites

Bornitz

Offergeld

et al. 2007

Laryngorhinootologie

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The insertion of the new silicone bordered micro joint into a TORP shaft provides an effective method to decrease the potentially damaging stapes footplate excursions after complete ossicular reconstruction. Limited deflections of the prosthesis shaft reduce the occurring forces on the stapes footplate as they partly bore the quasi static pressure changes. Thus, the micro joint can reduce the risk of prostheses dislocation and annular ligament damage and is additionally providing a proper sound transmission through the reconstructed middle ear. Moreover, the bionic modification of a TORP reflects the remaining possibilities for further improvements in prosthetic reconstruction.

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Titan-Prothesen im Mittelohr

Abstract: The superior acoustic properties of the delicate yet rigid low-weight titanium implants combined with excellent biocompatibility lead to a good hearing result if a meticulous surgical technique is employed. The easy handling makes it a pleasure to work with these protheses.

Cited by 49 publications

References 1 publication

Preliminary Hearing Results of Tympanomastoidectomies Using Titanium Prostheses: Scenario in a Developing Country

Preliminary Hearing Results of Tympanomastoidectomies Using Titanium Prostheses: Scenario in a Developing Country

Novel biological/biohybrid prostheses for the ossicular chain: fabrication feasibility and preliminary functional characterization

Experimentelle Untersuchungen zu Mittelohrimplantaten mit integriertem mikromechanischem Gelenk

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