Titanium(IV) Complexes of Unsymmetrical Schiff Bases Derived from Ethylenediamine and o‐Hydroxyaldehyde/Ketone and Their Anti‐microbial Evaluation

Uddin, Mohammad Nasir; Chowdhury, Didarul A.; Hossain, Kamrul

doi:10.1002/jccs.201200169

Cited by 22 publications

(7 citation statements)

References 14 publications

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“…The molar conductance values of the prepared zirconium (IV) complexes of the N, N′-bis (isatin) diamine schiff base ligands found very low which is depicted in Table I. The low molar conductivity of all complexes suggest their non-electrolytic character (Uddin et al 2012). This revealed that all ligands were covalently bonded with zirconium.…”

Section: Molar Conductancementioning

confidence: 93%

“…1 and 2, respectively. The spectra of the ligands should contain stretching bands for the azomethine group ((>C=Ngroup), C-N and C=O bonds at 1625-1582 cm -1 (Singh et al, 2012), 1020-1250 cm -1 (Uddin et al, 2012) and 1730-1750 cm -1 (Konstantinovic et al, 2015) regions, respectively. The vibrational frequency at 3150-3300 cm -1 (Ade et al, 2012) and 1460 cm -1 (Konstantinović et al, 2015) correspond stretching and bending vibration of N-H bond.…”

Section: Ft-ir Spectramentioning

confidence: 99%

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Synthesis and characterization of N, N′-bis (isatin) diamino zirconium (IV) complexes

Sarker¹,

Hossain²,

Bashir³

et al. 2019

Bangladesh J. Sci. Ind. Res.

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N, N′-bis (isatin) diamine schiff base ligands were synthesized by the condensation reaction of Isatin with various diamine (ethane-1,2-diamine, propane-1,3-diamine and hexane-1,6-diamine) in 2:1 molar ratios. These ligands were used to prepare Zr (IV) complexes. Prepared ligands and complexes were characterized by using conductance measurement, FT-IR, UV-Visible and 1 HNMR spectroscopy. The presence of FT-IR band for azomethine group supports the formation of ligand. Vibrational bands for Zr←N and Zr←O in complexes signify the coordination through O and N sites of ligands. 1 HNMR peak for NH moiety in ligand gets almost disappeared in complex reveals tautomerism of NH with nearby carbonyl oxygen due to the effect of complexation. The absence of peak above 500 nm in the electronic spectra indicates d 0 system of zirconium in complexes. The elemental analytical data was analogous to theoretical composition of ligands and complexes. The molar conductance values obtained for the complexes represent their non-electrolytic character.

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Section: Molar Conductancementioning

confidence: 93%

Section: Ft-ir Spectramentioning

confidence: 99%

Synthesis and characterization of N, N′-bis (isatin) diamino zirconium (IV) complexes

Sarker¹,

Hossain²,

Bashir³

et al. 2019

Bangladesh J. Sci. Ind. Res.

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“…The band for the C-N stretching frequency literally assigned in the region 1250-1020 cm -1 ( Uddin et al 2012). In the present work, the existence of peak at 1203.58 cm -1 , 1203.58 cm -1 and 1209.37 cm -1 showed the existence of the C-N stretching frequency in the ligands L 1 , L 2 ,L 3 , respectively and 1199.72 cm -1 , 1201.65cm -1 and 1201.65 cm -1 for complexes MoO 2 L 1 , MoO 2 L 2 and MoO 2 L 3 , respectively.…”

Section: Ftir Spectral Studymentioning

confidence: 99%

Molybdenum(VI) complexes of N, N′-bis isatin diamine Schiff base: Synthesis and characterization

Rahman,

Sarker,

Bashir

et al. 2023

Bangladesh J. Sci. Ind. Res.

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Schiff base ligand of N, N′-bis isatin diamine was synthesized from various diamine and isatin through condensation reaction in 1:2 molar ratio. Mo(VI) complexes of isatin-diamines were synthesized by the reaction between the sodium molybdate dehydrate and N,N' bis isatin diamines with the reflux method. The synthesized ligand and complexes were characterized using spectroscopic techniques. The FT-IR band of azomethine group at 1600- 1610 cm-1 indicated the formation of the ligand. The UV-vis spectra clearly indicated that the prepared complex is a genuine Mo(VI) with d0 electronic configuration. The formation of a coordination bond was revealed by the downfield chemical shift of the complex in the NMR data as compared to the ligand. The UV results were corroborated by molar conductance data, which demonstrated their non-electrolytic character. The experimental evidence primarily supported the synthesis of both ligands and corresponding Mo(VI) complexes. Bangladesh J. Sci. Ind. Res. 58(4), 201-208, 2023

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“…In a multitude of coordination compounds, titanium predominantly assumes the 4+ oxidation state. This is accomplished through oxo‐titanium (IV), TiO 2+ configuration, or non‐oxotitanium (IV), Ti 4+ ions formed by the loss of all 4s and 3d electrons 31,32 . Ti (IV) complexes have been extensively explored for their potential in antitumor, antimicrobial, anti‐coronavirus (SARS‐CoV‐2), and anticancer activities 33–36 .…”

Section: Introductionmentioning

confidence: 99%

“…This is accomplished through oxo-titanium (IV), TiO 2+ configuration, or non-oxotitanium (IV), Ti 4+ ions formed by the loss of all 4s and 3d electrons. 31,32 Ti (IV) complexes have been extensively explored for their potential in antitumor, antimicrobial, anti-coronavirus (SARS-CoV-2), and anticancer activities. [33][34][35][36] Titanocene dichloride and budotitane have successfully advanced to clinical trials, attributed to their cytotoxic potency and selectivity.…”

Section: Introductionmentioning

confidence: 99%

Antidiabetic and antioxidant studies of novel synthesized titanium (IV) complex: Design, synthesis, in‐silico docking and in‐vitro studies

Kaushal,

Kaur,

Kumar

et al. 2024

Applied Organom Chemis

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[{TiCl3}2(C3N3S3H)] (where C3N3S3H is Trithiocyanuric acid) was designed and synthesized by the reaction of TiCl4 and trithiocyanuric acid in 2:1 M ratio under stirring and refluxing condition using THF solvent. The synthesized Titanium (IV) complex was characterized by various spectroscopic techniques like FT‐IR, NMR, MASS, XRD, UV–visible spectrophotometer and elemental analysis (CHNSO). Moreover, in‐silico docking studies of the ligand and its Ti (IV) complex were carried out by AutoDockTools‐1.5.6 to study interactions of the complex under study with the receptor protein. Afterwards, both ligand and synthesized Ti (IV)complex were screened for the antioxidant and antidiabetic potential by in‐vitro method. The antioxidant potential was investigated by using DPPH (2,2‐diphenyl‐1‐picrylhydrazyl) radical scavenging assay where ligand exhibited moderate activity while Ti (IV) complex presented significant antioxidant activity. Following, alpha‐amylase enzyme inhibition was investigated using iodine‐starch inhibition assay. It was found that the ligand was inactive (showed no α‐amylase inhibition activity) while the Ti (IV)complex was a potent α‐amylase inhibitor. Furthermore, the experimentally obtained results were also complimented by the in‐silico results.

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Titanium(IV) Complexes of Unsymmetrical Schiff Bases Derived from Ethylenediamine and o‐Hydroxyaldehyde/Ketone and Their Anti‐microbial Evaluation

Cited by 22 publications

References 14 publications

Synthesis and characterization of N, N′-bis (isatin) diamino zirconium (IV) complexes

Synthesis and characterization of N, N′-bis (isatin) diamino zirconium (IV) complexes

Molybdenum(VI) complexes of N, N′-bis isatin diamine Schiff base: Synthesis and characterization

Antidiabetic and antioxidant studies of novel synthesized titanium (IV) complex: Design, synthesis, in‐silico docking and in‐vitro studies

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